| 脂蛋白a与老年人动脉钙化 |
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| 引用本文： | 许锋,赵迎,赵云博,满咏,李建斋.脂蛋白a与老年人动脉钙化[J].中国心血管杂志,1996,1(1):38-39. |
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| 作者姓名： | 许锋 赵迎 赵云博 满咏 李建斋 |
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| 作者单位： | 卫生部北京医院心内科
100730(许锋，赵迎，赵云博)，老年研究所
100730(满咏)，老年研究所 100730(李建斋) |
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| 摘 要： | 脂蛋白a(Lpa)是一种特殊的脂蛋白,其结构为LDL中的Apo B-100通过二硫键与1～2个Apo(a)联接而成.80年代末以来,人们研究发现Lp(a)水平升高与动脉粥样硬化密切相关.为探讨Lp(a)与主动脉和冠脉粥样硬化的关系,本文用回顾性方法对照比较了243例老年男性者CT所见的冠状动脉钙化和X线胸片和/或B超发现的胸,腹主动脉钙化与Lp(a)的关系.发现Lp(a)水平升高与冠状动脉钙化明显相关,而与主动脉钙化关系不大.
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| 关 键 词： | 脂蛋白(a) 动脉钙化 老年人 |
Lipoprotein(a) and Atherosclerosis in Old Male Patients |
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| Xu Feng,Zhao Ying,Zhao Yunbo,et al Division of Cardiology.Lipoprotein(a) and Atherosclerosis in Old Male Patients[J].Chinese Journal of Cardiovascular Medicine,1996,1(1):38-39. |
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| Authors: | Xu Feng Zhao Ying Zhao Yunbo Division of Cardiology |
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| Institution: | Xu Feng,Zhao Ying,Zhao Yunbo,et al Division of Cardiology,Department of Medicine Beijing Hospital,Beijing,100730 |
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| Abstract: | Lipoprotein (a) Lp (a)] is a special lipoprotein which is composed of one or two molecules of apolipoprotein(a) attached to apolipoprotein B-100 by a disulfide bond in a low density lipoprotein (LDL). Since the end of 1980's,it was found that increased level of Lp(a) is highly related to atherosclerosis. In order to study the relationship between Lp(a) and atherosclerosis of coronary artery and aorta,we reviewed the case of 243 old male patients and compared their Lp(a) levels with their calcification of coronary artery detected in CT scaning and of thoracic and abdominal aorta detected by chest X-ray and/or 2-DE ultrasound. We found that high lever of Lp(a) is strongly related to calcification of coronary artery,but has no obvious relationship with calcification of aorta. |
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| Keywords: | lipoprotein (a) low density lipoprotein atherosclerosis elders |
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