| 花粉症快速免疫治疗前后血清特异性抗体水平测定 |
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| 引用本文： | 王又孚 王旭东. 花粉症快速免疫治疗前后血清特异性抗体水平测定[J]. 中华耳鼻咽喉科杂志, 1997, 32(4): 216-217 |
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| 作者姓名： | 王又孚 王旭东 |
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| 作者单位： | [1]北京市第六医院耳鼻咽喉科 [2]中国医学科学院基础医学研究所 |
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| 摘 要： | 动态观察花粉症快速免疫治疗前后血清特异性ＩｇＥ、ＩｇＥ和ＩｇＧ４抗体的变化，对４９例进行快速免疫治疗的花粉症患者采用酶联免疫吸附测定法测定血清ＩｇＥ，ＩｇＧ和ＩｇＧ４。结果：花粉症患者血清特异性ＩｇＥ、ＩｇＧ和ＩｇＧ４较健康对照组明显升高（Ｐ〈０．００１和Ｐ〈０．０５），免疫治疗６周后ＩｇＧ和ＩｇＧ４抗体水平较治疗前明显升高（Ｐ〈０．００１和Ｐ〈０．０５），ＩｇＥ抗体无明显变化。证实快速免疫治疗在
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| 关 键 词： | 免疫疗法 花粉症 免疫球蛋白 抗体 测定 |
Changes in the levels of artemisia pollen specific antibodies during rush immunotherapy for pollinosis] |
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| Y Wang,X Wang,S Zheng. Changes in the levels of artemisia pollen specific antibodies during rush immunotherapy for pollinosis][J]. Chinese Journal of Otorhinolaryngology, 1997, 32(4): 216-217 |
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| Authors: | Y Wang X Wang S Zheng |
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| Affiliation: | Beijing Sixth Hospital. |
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| Abstract: | Artemisa pollen-specific immumoglobulins (IgG4, IgG and IgE) were evaluated by means of ELISA during rush immunotherapy in 49 patients with pollinosis. The results showed that six weeks after the beginning of immunotherapy, the levels of specific IgG4(P < 0.05) and IgG (P < 0.001) antibodies were significantly higher than those of patients prior to receiving rush immunotherapy. These results suggest that rush immunotherapy may result in a rapid increase in IgG antibody levels, and high specific IgG level may implicate a clinical improvement in allergic patients due to the rush immunotherapy. |
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