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不孕症自身抗体HCGA与生殖激素水平关系的研究
引用本文:黄新亮,洪亮.不孕症自身抗体HCGA与生殖激素水平关系的研究[J].皖南医学院学报,2005,24(3):173-175.
作者姓名:黄新亮  洪亮
作者单位:皖南医学院微,生物学与免疫学教研室,安徽,芜湖,241001
摘    要:目的 研究不孕症妇女血清抗 HCG抗体(anti humanchorionicgonadotropineantibody ,HCGA)与生殖激素水平的关系。方法 用放射免疫法检测不孕症妇女血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2 )、孕酮(P)水平,用ELISA间接法定性检测HCGA。结果 HCGA阳性组(2 5例)FSH水平显著高于HCGA阴性组(73例) ,而LH、E2 、P水平显著低于HCGA阴性组。结论 HCGA可能是引起生殖激素水平改变而导致不孕的重要因素之一。

关 键 词:不孕症  生殖激素  绒毛膜促性腺激素(HCGA)
文章编号:1002-0217(2005)03-0173-03
收稿时间:2004-10-27
修稿时间:2004年10月27

Study on the correlation between anti-human chorionic gonadotropin antibodies and the levels of reproductive hormone in infertility
HUANG Xin-liang,HONG Liang.Study on the correlation between anti-human chorionic gonadotropin antibodies and the levels of reproductive hormone in infertility[J].Acta Academiae Medicinae Wannan,2005,24(3):173-175.
Authors:HUANG Xin-liang  HONG Liang
Abstract:Objective To explore the correlation between anti-human chorionic gonadotropin antibody(HCGA) and the levels of reproductive hormone in women with infertility. Methods Levels of FSH, LH, E2 and P were determined by RIA and qualitative examination of serum HCGA was measured with ELISA. Results In women with infertility, the serum levels of FSH with positive HCGA(n=25) were obviously higher than those with negative HCGA(n=73)while the levels of E2, P and LH were obviously lower. Conclusion HCGA may be one of the main factors for women with infertility in changing the levels of reproductive hormone.
Keywords:infertility  reproductive hormone  anti-human chorionic gonadotropin antibody
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