| 4种穿心莲内酯中药注射液不良反应分析及原因探索 |
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| 引用本文： | 向东,汪梦蝶,王文清,施春阳,谢雪佳,方建国. 4种穿心莲内酯中药注射液不良反应分析及原因探索[J]. 中国中药杂志, 2016, 41(12): 2350-2355 |
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| 作者姓名： | 向东 汪梦蝶 王文清 施春阳 谢雪佳 方建国 |
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| 作者单位： | 华中科技大学 同济医学院 附属同济医院 药学部, 湖北 武汉 430030,华中科技大学 同济医学院 附属同济医院 药学部, 湖北 武汉 430030,华中科技大学 同济医学院 附属同济医院 药学部, 湖北 武汉 430030,华中科技大学 同济医学院 附属同济医院 药学部, 湖北 武汉 430030,华中科技大学 同济医学院 附属同济医院 药学部, 湖北 武汉 430030,华中科技大学 同济医学院 附属同济医院 药学部, 湖北 武汉 430030 |
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| 摘 要： | 对中国期刊全文数据库(CNKI)、万方数据库及维普中文科技期刊数据库所收录的近15年4种穿心莲内酯注射液的文献进行检索,对报道的穿琥宁、炎琥宁、喜炎平、莲必治注射剂的不良反应(ADR)病例进行分类统计分析,纳入分析的文献共194篇,病例3 479例。从患者的性别、年龄、原发疾病情况、出现ADR的时间、临床表现、过敏史、给药剂量、愈后及合并用药情况等分析和对比4种穿心莲内酯注射剂ADR的临床特点和发生规律,为临床安全合理使用穿心莲内酯类注射剂提供有价值的参考。
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| 关 键 词： | 穿心莲内酯 不良反应 中药注射剂 安全性研究 |
| 收稿时间： | 2016-01-14 |
Analysis and exploration on adverse reactions of four kinds of andrographolide injections |
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| XIANG Dong,WANG Meng-die,WANG Wen-qing,SHI Chun-yang,XIE Xue-jia and FANG Jian-guo. Analysis and exploration on adverse reactions of four kinds of andrographolide injections[J]. China Journal of Chinese Materia Medica, 2016, 41(12): 2350-2355 |
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| Authors: | XIANG Dong WANG Meng-die WANG Wen-qing SHI Chun-yang XIE Xue-jia FANG Jian-guo |
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| Affiliation: | Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China,Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China,Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China,Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China,Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China and Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| Abstract: | Concerned literature on four kinds of andrographolide injections in recent 15 years were searched in CNKI, Wanfang and VIP databases. The adverse drug reaction(ADR) cases of Chuanhuning, Yanhuning, Xiyanping and Lianbizhi injections were classified and analyzed statistically, including a total of 194 articles and 3 479 cases. The ADR clinical characteristics and occurrence regularity of these four andrographolide injections were analyzed and compared from the gender, age, primary disease, emergence time of ADR, clinical manifestation, allergy history, dosage, prognosis and combined medication of the patients. It is useful to provide valuable references for rational use of these andrographolide injections in clinical practice. |
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| Keywords: | andrographolide adverse reactions traditional Chinese medicine injections safety study |
| 本文献已被 CNKI 等数据库收录！ |
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