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高选择性环氧化酶—2抑制剂的进展与评价
引用本文:张石革,宋菲,马国辉.高选择性环氧化酶—2抑制剂的进展与评价[J].中国医院用药评价与分析,2003,3(5):277-280.
作者姓名:张石革  宋菲  马国辉
作者单位:北京大学北京积水潭医院,北京市,100035
摘    要:目的 :介绍高选择性环氧化酶 - 2抑制剂———昔布类药物进展 ,并评价其临床疗效 ,以供临床参考。方法 :查阅国内、外近期相关文献进行分析、评价。结果与结论 :昔布类高选择性环氧化酶 - 2抑制剂进展十分迅速 ,对环氧化酶 - 2的选择性高 ,在治疗骨关节炎和类风湿性关节炎、关节痛、术后疼痛和肿瘤上展现了良好的治疗前景

关 键 词:高选择性环氧化酶-2抑制剂  环氧化酶-2  进展  临床应用
文章编号:1672-2124(2003)05-0277-04
修稿时间:2003年9月25日

Progress and Clinical Evualuation on Highly Selective Inhibitor of Cyclooxygenase- 2(Xib)
ZHANG Shige,SONG Fei,MA Guohui.Progress and Clinical Evualuation on Highly Selective Inhibitor of Cyclooxygenase- 2(Xib)[J].Evaluation and Analysis of Drug-Use in Hospital of China,2003,3(5):277-280.
Authors:ZHANG Shige  SONG Fei  MA Guohui
Abstract:OBJECTIVE: To summarize the aspect of clinical application and progress on highly selective inhibitor of cyclooxygenase-2(Xib).METHODS:To collecte med ical literatures in recent years at home and abroad. RESULTS & CONCLUSION:Advanc e in highly selective inhibitor of cyclooxygenase-2(Xib) has been swiftly in rec ent years,with higher selectivity to COX-2 highly selective inhibitor of cycl ooxygenase-2 plays an important role in the treatment of osteoarthritis and rheu matoid arthritis,arthralgia,tumors and pain after operation.
Keywords:highly selective inhibition of COX-2  cyclooxygenase- 2  progress  clinical application
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