生长素治疗小儿烧伤的临床价值

目的　探讨生长素对小儿烧伤创面愈合、感染的发生率、住院日数以及预后的作用。方法　随机选择烧伤面积大于 2 5 % ,Ⅲ°烧伤面积大于 10 %的重度烧伤患儿 2 4例 ,将其随机分为两组 ,重组人生长激素组(rhGHgroup)每日上午 9时肌注rhGH 0 3U/kg,共治疗 8天 ,对照组 (controlgroup)不给rhGH治疗 ,只给抗生素进行抗感染治疗 ,记录两组植皮区和供皮区创面愈合时间以及住院日数 ,计算烧伤后第 2 8天全身创面愈合率。结果　rhGH组精神状态和食欲情况优于对照组 ,植皮区和供皮区创面愈合时间、住院日数等均少于对照组。结论　烧伤后早期使用rhGH有利于改善全身状况 ,促进创面愈合 ,减少并发症

The effect of growth hormone on wound healing rate in children burns

Objective To determine the wound healing effect of rhGH in children burn patients.Methods 24 children with burn wounds covering over 25% of total body surface(TBSA) were studied.rhGH group patients were given rhGH intramuscularly in the dose of 0 3U/kg,at 9 each morning for 8 days beginning from PODI.The patients in control group were not given rhGH.All the patients received eschar excision within 5 days after burn,and the excision wounds were covered with autologous skin pulp grafting.Healing time of burn wound area and donor site was recorded.Wound healing rate was assessed at 28th day after burn.Results The healing time of autologous skin pulp grafting and donor site,and the length of hospitalization in GH group patients were significantly shorter than those in control group.Conclusion rhGH could enhance the wound healing rate,and reduce the hospitalization time of severe burn children.