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An antiserum to locust adipokinetic hormone reveals a novel peptidergic system in the rat central nervous system
Authors:Catherine A. Sasek   Paula A. Schueler   William S. Herman  Robert P. Elde  
Affiliation:1. Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho Uji, Kyoto 611-0011, Japan;2. Research Unit for Physiological Chemistry, C-PIER, Kyoto University, Kyoto 606-8501, Japan;3. Health Care Research Center, R&D Division, Nisshin Pharma Inc., 5-3-1 Tsurugaoka, Fujimino City, Saitama 356-8511, Japan
Abstract:Using an antiserum to locust adipokinetic hormone I, a novel peptidergic system was identified in the rat central nervous system. Immunoreactive fibers were present in the hypothalamic median eminence and periventricular nucleus and the spinal cord dorsal horn, intermediolateral cell column and sacral parasympathetic nucleus. Immunoreactive cells were present in the dorsal gray commissure of lumbosacral spinal cord, the hypothalamic periventricular nucleus and cerebral cortex.
Keywords:novel peptide   immunohistochemistry   adipokinetic hormone I (AKH)-like   rat central nervous system
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