| 中药白花前胡根中香豆素白花前胡素(E)的分离鉴定 |
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| 引用本文： | 叶锦生,张涵庆,袁昌齐.中药白花前胡根中香豆素白花前胡素(E)的分离鉴定[J].药学学报,1982,17(6):431-434. |
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| 作者姓名： | 叶锦生 张涵庆 袁昌齐 |
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| 作者单位： | 江苏省植物研究所 南京
(叶锦生，张涵庆)，江苏省植物研究所 南京(袁昌齐) |
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| 摘 要： | 从白花前胡(Peucedanum praeruptorum Dunn)根的醚提取物中除分得已知香豆素白花前胡丙素和另一种结晶外,还分得一种具有生理活性的香豆素单体,命名为(+)白花前胡素(E)(+)praeruptorin E]。经元素分析、紫外、红外、质谱、核磁、气相及水解产物的鉴定,证明白花前胡素(E)为(+)3′-当归酰基-4′-异戊酰基-顺式-凯林酮(+)3′-angeloyl-4′-isovalerylcis-khellactone,此香豆素对小白鼠具有耐缺氧作用。关于其他成分,将另有报告。
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| 关 键 词： | 白花前胡素丙 (+)白花前胡素E |
| 收稿时间： | 1981-03-30 |
ISOLATION AND IDENTIFICATION OF COUMARIN PRAERUPTORIN E FROM THE ROOT OF THE CHINESE DRUG PEUCEDANUM PRAERUPTORUM DUNN (UMBELLIFERAE) |
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| YE Jin-sheng,ZHANG Han-qing and YUAN Chang-qi.ISOLATION AND IDENTIFICATION OF COUMARIN PRAERUPTORIN E FROM THE ROOT OF THE CHINESE DRUG PEUCEDANUM PRAERUPTORUM DUNN (UMBELLIFERAE)[J].Acta Pharmaceutica Sinica,1982,17(6):431-434. |
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| Authors: | YE Jin-sheng ZHANG Han-qing and YUAN Chang-qi |
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| Abstract: | A pharmacologically active new compound, praeruptorin E and two known praeruptorin C and crystal (Ⅱ) were first isolated from the root of the Chinese drug Peucedanum praeruptorum Dunn.The structure of praeruptorin E was elucidated as(+)3'-angeloyl-4'-isovalerylcis-khellactone by spectral (UV; IR, MS, NMR) and chemical (hydrolysis) studies Praeruptorin E was shown to increase tolerance to anoxia in intact mice. |
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| Keywords: | Praeruptorin C (+) Praeruptorin E |
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