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哌替啶联合异丙嗪在局麻下鼻内镜鼻窦手术中的应用
引用本文:邓鹏,耿宛平,李龙英,彭月坤.哌替啶联合异丙嗪在局麻下鼻内镜鼻窦手术中的应用[J].华夏医学,2008,21(3).
作者姓名:邓鹏  耿宛平  李龙英  彭月坤
作者单位:1. 广西医科大学第五附属医院,广西,柳州,545001
2. 桂林医学院附属医院,广西,桂林,541001
摘    要:目的:观察哌替啶配伍异丙嗪在鼻窦内窥镜手术中的作用。方法:选择须行鼻内镜鼻窦手术的患者64例,随机分为观察组32例,对照组32例。观察组在局部麻醉完成后手术开始时肌注哌替啶100mg 异丙嗪50mg;对照组不用哌替啶 异丙嗪,病变严重程度及手术范围两组相同。结果:术中镇痛、镇静观察组效果较好,与对照组比较有差异(P<0.05),术中、术后观察组与对照组的平均动脉压和心率有差异(P<0.05)。结论:哌替啶配伍异丙嗪在鼻内窥镜手术中有良好效果,能显著改善患者的手术耐受性。

关 键 词:哌替啶  异丙嗪  内镜术

Endoscopic sinus surgery under local anaesthesia with intramuscular injection of pethidine and promethazine
DENG Peng GENG Wan-ping LI Long-ying.Endoscopic sinus surgery under local anaesthesia with intramuscular injection of pethidine and promethazine[J].Acta Medicinae Sinica,2008,21(3).
Authors:DENG Peng GENG Wan-ping LI Long-ying
Institution:DENG Peng GENG Wan-ping LI Long-ying Department of Otolaryngology,The Fifth Affiliated Hospital of Guangxi Medical University,Liuzhou 545001,China
Abstract:Objective:To investigate the effect of pethidine and promethazine IM during the period of endoscopic sinus surgery.Methods:Sixty-four patients underwent endoscopic sinus surgery were randomly assigned to receive pethi- dine and promethazine before operation(n=32)or no pre-operative medication(control group,n=32).Pethidine 100mg and promethazine 50mg were intramuscularly injected.Results:The analgesic effects and calmness effects dur- ing the operation were significantly different in favour of pethidine and promethazine group(P<0.05).The Mean ar- terial pressure and the heart rate was significantly different between two groups during/after the operation(P<0.05).Conclusion:Intramuscular injection of pethidine and promethazine before endoscopic sinus surgery has favourable analgesic effects and calmness effects.
Keywords:Pethidine  Promethazine  endoscopic surgery
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