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正常妊娠与子宫内膜异位症中HLA-G蛋白表达的差异
引用本文:柳玲,朱晓明.正常妊娠与子宫内膜异位症中HLA-G蛋白表达的差异[J].中国优生与遗传杂志,2007,15(7):13-13,15.
作者姓名:柳玲  朱晓明
作者单位:1. 安徽省凤阳县第一人民医院妇产科,233100
2. 第四军医大学唐都医院妇产科
摘    要:目的在蛋白水平检测人类白细胞抗原-G(HLA—G)在子宫内膜异位症(EM)在位与异位内膜组织中的表达。方法选取卵巢子宫内膜异位囊肿患者30例(实验组),非子宫内膜异位症患者30例(对照组),应用Western blot方法检测实验组及对照组在位与异位内膜组织中HLA—G蛋白的表达差异。结果HLA—G蛋白在实验组在位与异位内膜组织中的表达均明显高于对照组(P〈0.05)。结论HLA—G蛋白表达的异常可能与EM发病有关。

关 键 词:子宫内膜异位症  人类白细胞相关抗原-G
文章编号:1006-9534(2007)07-0013-02
收稿时间:2006-12-22
修稿时间:2006-12-22

The different expression of HLA-G protein in placentas between endometriosis and normal pregnant women
LIU Ling,ZHU Xiao-ming.The different expression of HLA-G protein in placentas between endometriosis and normal pregnant women[J].Chinese Journal of Birth Health & Heredity,2007,15(7):13-13,15.
Authors:LIU Ling  ZHU Xiao-ming
Abstract:Objective:To investigate human leukocyte antigen-G(HLA-G) protein expression in the endometrium of endometriosis(EM).Methods:30 women with ovarian endometriosis(OEM),30 women without EM were recruited as study group and control group,respectively.Western blot was used for quantitative detection of the difference on HLA-G protein expression in the endometrium between two groups.Results:HLA-G protein expression of OEM group was significantly higher than that in the control group.Conclusion:Higher HLA-G protein may be related to the pathomechanism of EM.
Keywords:Western blot
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