胸腔闭式引流加高渗糖、重组人白介素-2及利多卡因联合胸腔内注入治疗自发性气胸及复发的临床研究 |
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引用本文: | 翟乃璞,翟淼浡,陈起帅,赵民刚,蒲哲,李旭光,刘彦龙.胸腔闭式引流加高渗糖、重组人白介素-2及利多卡因联合胸腔内注入治疗自发性气胸及复发的临床研究[J].现代保健,2013(24):115-116. |
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作者姓名: | 翟乃璞 翟淼浡 陈起帅 赵民刚 蒲哲 李旭光 刘彦龙 |
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作者单位: | 山东省淄博市淄川区医院,山东淄博255100 |
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摘 要: | 目的:探讨自发性气胸胸管内注入设定药物与气胸复发、住院天数及医疗费用的相关性。方法:对60例自发性气胸患者,胸腔闭式引流后X线检查证实肺基本复张后,随机分为对照组(单纯胸腔闭式引流),治疗组(经胸管内注入利多卡因、高渗糖及重组人白介素-2)。随访2~10年。结果:治疗组治愈28例,复发2例,总有效率95%,复发率6%,住院天数平均(10±1)d,住院费用(4000±316)元。对照组患者治愈16例,14例复发,总有效率53%,复发率为46%,住院平均天数为(18±2)d,费用(8000±615)元。两组比较,有效率、复发率、住院天数及住院费用均差异有统计学意义(P〈0.01)。结论:利多卡因、高渗糖及重组人白介素-α联合胸腔内注入是治疗及预防复发、减少副作用、缩短住院时间、降低医疗费用的有效方法。
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关 键 词: | 自发性气胸 胸腔闭式引流 胸膜粘连固定 复发 住院时间 医疗费用 |
Clinical Research for the Spantaneous Pneumothorax Treatment and Recurrence Prevention Combined with Thoracic Close Drainage and Intraluminal Injection of Lidocaine Heperosmotic Glucose and Recombinant Human IL-2 |
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Institution: | ZHAI Nai-pu Zichuan Hospital,Zibo 255100,China,ZHAI Miao-bo,CHEN Qi-shuai,et al. |
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Abstract: | Objective:To investigate the relationship between chest tube injected in setting drug and recurrence of pneumothorax,hospital stays,and hospitalization costs in patients with spontaneous pneumothorax. Method:60 patients suffering from spantaneous pneumothorax with chest tube injected were included. After lungs recruitment,60 patients were randomly assigned either a treatment program that included intraluminal injection of Lidocaine heperosmotic glucose and recombinant Human IL-2 or one that only used thoracic close drainage therapy. Follow up for 2-10 years. Result: In the treatment group,the patients who recovered accounted for 95%(28 cases),and relapsed for 6%(2 cases). The mean hospital stay and hospital costs were 10 days,and 4000 yuan,respectively. While in the control group,the cure rates and recurrence rates were 53%(16 cases),and 46%(14 cases),respectively. The mean hospital stay was 18 days,and the hospital cost was 8000 yuan. Conclusion:There was statistically significant effect that using intraluminal injection of Lidocaine,heperosmotic glucose and recombinant Human IL-2 to treatment and prevention of recurrence for the spantaneous pneumothorax,reduce side effects,shorter hospital stays,lower medical costs. |
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Keywords: | Spontaneous pneumothorax Thoracic close drainage Pleural adhesion fixed Recurrence Hospital stays Hospitalization costs |
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