阿奇霉素联合脾氨肽治疗小儿哮喘38例疗效观察

目的：观察阿奇霉素联合脾氨肽治疗小儿哮喘的临床疗效和安全性。方法：将76例支气管哮喘患儿随机分为观察组和对照组各38例,两组均给予常规治疗,对照组给予阿奇霉素口服,10mg/（kg·d）;观察组在对照组用药基础上给予脾氨肽口服冻干粉,1支/d,一月后改为隔日1支;2个月后比较两组疗效。结果：观察组有效率92.1%,明显高于对照组的81.6%（P〈0.05）;观察组的症状体征消失时间和住院时间也明显优于对照组（P〈0.05）。结论：阿奇霉素联合脾氨肽治疗小儿哮喘疗效显著,患儿恢复快且不良反应少,值得在临床推广。

Effect Observation of Azithromycin Combined with Spleen Aminopeptidase for 38 Children with Asthma

Objective：To observe the clinical effect of azithromycin combined with spleen aminopeptidase for the treatment of asthma in children. Method：76 patients were randomly divided into two groups：test group and control group,38 cases in each group.The two groups were given conventional treatment.The control group was given 10 mg/kgod of azithromycine tablets. The test group was given spleen aminopeptidase on the base of control group. Comparing the clinical effects of the different groups in a 2-month course.Result：The total effective rate of test group was 92.1%,it was significantly higher than that of control group（ P〈0.05）. Disappearance time of symptoms and signs and hospital stay of the test group were significantly shorter than the that of control group（ P〈0.05）.Conclusion：The clinical effect of azithromycin combined with spleen aminopeptidase on the treatment for asthma in children is satisfactory.The patients recovery faster and less adverse reactions,is worthy of clinical use.