| 紫外分光光度法测定间尼索地平的含量 |
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| 引用本文： | 张兰桐,和悦,周月绵,赵德运,张凌燕.紫外分光光度法测定间尼索地平的含量[J].河北医科大学学报,1999,20(3):149-151. |
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| 作者姓名： | 张兰桐 和悦 周月绵 赵德运 张凌燕 |
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| 作者单位： | 河北医科大学药学院药物分析教研室,石家庄,050017 |
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| 摘 要： | 间－尼索地平为国家一类新药。为控制药的质量，采用了两种紫外分光光度法对其进行含量测定。方法分别采用标准曲线法和标准吸收系数法测定间－尼索地平的含量。结果标准曲线法测定间－尼索地平的平均回收率和相对标准偏差分别为１００．２％、０．６４％。
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| 关 键 词： | 间尼索地平/分析 分光光度法 紫外线/方法 |
DETERMINATION OF m-NISOLDIPINE BY ULTRAVIOLET SPECTROPHOTOMETRY |
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| Zhang Lantong,He Yue,Zhou Yuemian,Zhao Deyun,Zhang Lingyan.DETERMINATION OF m-NISOLDIPINE BY ULTRAVIOLET SPECTROPHOTOMETRY[J].Journal of Hebei Medical University,1999,20(3):149-151. |
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| Authors: | Zhang Lantong He Yue Zhou Yuemian Zhao Deyun Zhang Lingyan |
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| Institution: | Shijiazhuang 050017 |
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| Abstract: | ObjectiveTo control the quality of m-Nisoldipine,a new antihypertensive drug,two methods were used for determination of m-Nisoldipine in raw material and tablets.MethodsBoth the calibration curve and specific absorptivity were adopted to measure m-Nisoldipine.ResultsIn the method of calibration curve,the average recovery and relative standard deviation were respectively 100.2 %, 0.64 %,and in the method of specific absorptivity,the average recovery and relative standard deviation were respectively 99.96 %, 0.93 %.ConclusionIn the determination of m-Nisoldipine,both methods are accurate and simple without obvious difference,and can be used as standard methods for quality control of m-Nisoldipine. |
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| Keywords: | m-Nisoldipine/anal spectrophotometry ultraviolet/methods |
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