合并糖代谢异常的不稳定型心绞痛患者单核细胞趋化蛋白1水平与不稳定性斑块的关系

目的明确合并糖代谢异常的不稳定型心绞痛患者单核细胞趋化蛋白1水平与不稳定性斑块的关系。方法连续选取本院冠状动脉造影和冠状动脉内超声明确诊断的不稳定型心绞痛患者86例,合并糖代谢异常的不稳定型心绞痛患者36例入选糖代谢异常组,无糖代谢紊乱的不稳定型心绞痛患者50例入选糖代谢正常组,以酶联免疫吸附法测定血浆炎性因子水平,比较两组不稳定型心绞痛患者间炎性因子水平以及与冠状动脉易损斑块形态学特征的相关性。结果在不稳定型心绞痛患者中,合并糖代谢异常组单核细胞趋化蛋白1水平明显高于糖代谢正常组。血清单核细胞趋化蛋白1水平与不稳定型心绞痛患者冠状动脉斑块体积存在明显的相关性。结论合并糖代谢异常的不稳定型心绞痛患者具有更高的血清单核细胞趋化蛋白1水平,并与冠状动脉易损斑块体积大小相关。

Monocyte Chemoattractant Protein-1 Level and The Relation of Coronary Vulnerable Plaque in Patients with Abnormal Glycometablism

Aim To evaluate monocyte chemoatlractant protein-1 level and the relation of the vascular inflammation factor and coronary vulnerable plaque in the patients with abnormal glycometablism.Methods 86 unstable angina pectoris patients with the coronary vulnerable plaque undergoing coronary angiogram and IVUS were consecuted.36 patients with abnormal glycometablism entered the diabetes group,50 patients with no diabetes in the control group.The serum inflammation factors were tested.Results According to the pati...