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Early side effects of radiation treatment for head and neck cancer
Authors:I Brook
Institution:1. Radiation oncology department, Okmeydani education and research hospital, Istanbul, Turkey;2. Department of radiation oncology and particle therapy, National cancer centre hospital East, Chiba, Japan;3. Course of advanced clinical research of cancer, Graduate school of medicine, Juntendo University, Tokyo, Japan;1. Department of Radiation Oncology, HFR Fribourg – Cantonal Hospital, Chemin des Pensionnats 2-6, 1708 Fribourg, Switzerland;2. Department of Radiation Oncology, Inselspital, University Hospital Bern, Freiburgstrasse 18, 3010 Bern, Switzerland;3. Department of Medical Oncology, HFR Fribourg – Cantonal Hospital, Chemin des Pensionnats 2-6, 1708 Fribourg, Switzerland;4. Department of Gynecology and Obstetrics, HFR Fribourg – Cantonal Hospital, Chemin des Pensionnats 2-6, 1708 Fribourg, Switzerland;1. Department of Thoracic surgery, Cancer hospital of the University of Chinese Academy of Sciences (Zhejiang cancer hospital), Hangzhou, Zhejiang, China;2. Department of Radiotherapy, Cancer hospital of the University of Chinese Academy of Sciences (Zhejiang cancer hospital), 1, Banshandong road, 310022 Hangzhou, Zhejiang, China;3. Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, Zhejiang, China;4. The Second Clinical Medical College, Zhejiang Chinese Medical University;1. Shanghai Jiao Tong University School of Medicine, Shanghai, China;2. Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030 China;3. Department of Statistics, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;1. Centre de radiothérapie Marie-Curie, 159, boulevard Maréchal-Juin, 26000 Valence, France;2. Hospices civils de Lyon, 69000 Lyon, France;1. Department of radiation oncology, institut de cancérologie de l’ouest site Saint-Herblain, boulevard du Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France;2. Department of medical physics, institut de cancérologie de l’ouest site Saint-Herblain, boulevard du Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France;3. Department of urology, hôpital privé Océane, 3, rue du Dr-Joseph-Audic, 56000 Vannes, France;4. Department of urology, centre hospitalier universitaire de Nantes, place Ricordeau, 44000 Nantes, France;5. Department of urology, clinique Saint-Augustin, 1, rue Eugene-Tessier, 44000 Nantes, France
Abstract:Purpose of this review of medical literature is to present the immediate side effects of radiation therapy for head and neck cancer and their treatment. The likelihood and severity of these immediate side effects depends on a number of factors, including the total dose of radiation delivered, over what time it was delivered and what parts of the head and neck received radiation. Early side effects include: inflammation of the oropharyngeal mucosa (mucositis), painful swallowing (odynophagia), difficulty swallowing (dysphagia), hoarseness, lack of saliva (xerostomia), orofacial pain, laryngeal radionecrosis, dermatitis, hair loss, nausea, vomiting, inadequate nutrition and hydration, and weight loss. These complications can interfere with, and delay treatment. Most of these side effects generally dissipate over time. In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients’ health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.
Keywords:Radiation  Side effects  Pain  Cancer  Lymphedema  Mucositis  Radiothérapie  Effets secondaires  Douleur  Cancer  Lymph?dème  Mucite
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