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Economic Evaluation of Vaccines: Belgian Reflections on the Need for a Broader Perspective
Authors:Lieven Annemans  Philippe Beutels  David E. Bloom  Wilfried De Backer  Olivier Ethgen  Jeroen Luyten  Philippe Van Wilder  Lander Willem  Steven Simoens
Affiliation:1. Department of Public Health and Primary Care, Ghent University, Ghent, Belgium;2. Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium;3. Harvard T.H. Chan School of Public Health, Boston, MA, USA;4. Department of Pneumology, University of Antwerp, Antwerp, Belgium;5. Department of Public Health, Epidemiology and Health Economics, Faculty of Medicine, University of Liège, Liège, Belgium;6. Department of Public Health and Primary Care, Leuven Institute for Healthcare Policy, KU Leuven, Leuven, Belgium;7. Université Libre de Bruxelles, School of Public Health, Brussels, Belgium;8. Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium;9. Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
Abstract:ObjectivesThe standard framework of economic evaluation of health programs, which is increasingly used for policy funding decisions, is insufficiently equipped to reflect the full range of health and economic benefits conferred by vaccines and thus undervalues vaccination.MethodsIn 2019, a group of Belgian health economic and clinical experts, supported by 2 senior international vaccination experts (1 American, 1 Belgian), convened 4 roundtable meetings to highlight which particular value elements of vaccination remain neglected in economic evaluations.ResultsThey concluded that the standard economic evaluation framework fails to reflect the full value of vaccination with respect to prevention of complications linked to some vaccine-preventable diseases, health gains for caregivers, herd effects, changes in exposure to and distribution of serotypes, the effect on antimicrobial resistance, productivity gains for caregivers and patients, and the distributive implications of vaccination programs.ConclusionsHere, suggestions are made regarding how these shortcomings can be addressed in future economic evaluations of vaccines and how a more level playing field between vaccines and other health programs can be created.
Keywords:community benefits  economic evaluation  equity  vaccine  value elements  productivity
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