针刺结合雷火灸治疗女性黄褐斑的临床研究

目的 观察针刺结合雷火灸治疗黄褐斑的临床疗效。方法 将78例女性黄褐斑患者随机分为治疗组和对照组，每组39例。治疗组采用针刺配合雷火灸治疗，对照组采用口服维生素Ｃ及维生素Ｅ治疗，12周为1个疗程，观察2组患者治疗前后皮损面积、皮损颜色、雌激素(E₂)、孕激素(P)等指标的变化。结果 治疗后治疗组、对照组总有效率分别为82.1%和61.5%，治疗组疗效优于对照组(P<0.05)；治疗组皮损改善情况优于对照组(P＜0.05)；2组E₂水平降低，P水平提高(P<0.05~0.01)，治疗组优于对照组(P＜0.05)；治疗组在改善患者皮肤病生活指数上明显优于对照组(P＜0.05)。结论 针刺结合雷火灸治疗黄褐斑疗效优于西药组，且能调节E₂和P水平，值得临床推广。 

Clinical Effects Observation of Combined Acupuncture and Thunder-fire Moxibustion in the Treatment of Female Patients with Chloasma

OBJECTIVE To observe the clinical effects of the combined acupuncture and thunder-fire moxibustion in the treatment of female patient with chloasma. METHODS Seventy-eight female patients with chloasma were randomly divided into the treatment group and the control group， 9 cases in each group. The treatment group was treated with the combined acupuncture and thunder-fire moxibustion， and the control group was treated with orally taking VitC and VitE， 12 weeks as a course. Indicator changes such as skin lesion area， skin color， estrogen estradiol (E₂) and progesterone (P) were observed in two groups before and after treatment. RESULTS The total effective rate of the treatment group and the control group was 82.1% and 61.5% respectively after the treatment， and the therapeutic effect of the treatment group was better than that of the control group(P<0.05). Skin lesions improvement in the treatment group was better than that of the control group(P<0.05). E₂ levels decreased in two groups and P levels in two groups increased(P<0.05~0.01)， and the treatment group was better than the control group(P<0.05). Dermatology life quality index improvement in the treatment group was significantly better than that of the control group(P<0.05). CONCLUSION The combined acupuncture and thunder-fire moxibustion treatment has better curative effects than western medicine treatment group， and it can regulate E₂ and P levels， which deserves wild application in clinical practice.