维生素D对骨关节炎作用的进展

骨关节炎(OA)是我国中老年人常见病、多发病之一，疾病使软骨破坏、软骨下骨质病变和关节周围骨质增生，最终导致关节疼痛、功能障碍甚至是畸形，影响患者活动能力。维生素D具有参与钙磷代谢、改善成骨细胞的活性、促进骨基质的骨化、增加骨密度以及关节软骨的转化等功能，对骨骼健康十分重要。但人体维生素D水平对OA的影响尚未明确，本文就维生素D与OA发展、关节疼痛症状、关节置换术后功能恢复以及补充维生素D后治疗效果等方面相关研究作一综述。

Progress in effects of vitamin D on osteoarthritis

Osteoarthritis (OA), as characteristics are the loss of cartilage and concurrent changes in subchondral bone, is a common public health issue with Chinese people, resulting in joint pain and subsequent disability of the patients. Vitamin D plays an important role in calcium phosphorus metabolism, bone health and musculoskeletal function. However, the relationship between vitamin D and OA has not been clarified, and the goal of this literatures review is to determine relationship between vitamin D and OA.