Effects of chick embryo homogenate and cyclophosphamide on the growth and metastatic spread of pliss sarcoma in rats: A comparative study |
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| Authors: | S. Yu. Rodionov N. A. Pak V. I. Kulakov G. T. Sukhikh E. M. Molnar |
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| Affiliation: | (1) Bioterapiya Clinical Research Center, Novosibirsk;(2) International Institute of Biological Medicine, Moscow |
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| Abstract: | A chick embryo homogenate inhibited the growth and metastatic spread of Pliss sarcoma in rats and prolonged their survival. The histological picture of extensive tumor tissue necrosis with a characteristic infiltration by leukocytes and macrophages suggests that the mechanism underlying the antineoplastic action of the embryonal homogenate is quite different from that of cyclophosphamide and involves the activation of cell-mediated immunity. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N o 12, pp. 610–612, December, 1995 |
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| Keywords: | Pliss sarcoma embryonal homogenate cyclophosphamide cell-mediated immunity |
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