ω-3多不饱和脂肪酸对结肠癌的影响

ω-3多不饱和脂肪酸（ω-3PUFA）主要来源于鱼油，是细胞结构和功能重要组成成分，对细胞免疫应答调节和抑制发挥重要作用。ω-3PUFA可通过影响细胞膜脂质组成、调控脂类代谢水平及细胞内基因编码等多种途径，阻滞结肠癌细胞生长周期、抑制细胞增殖、促进细胞分化和诱导癌细胞凋亡，显著抑制结肠癌生长和转移，还可改善肿瘤恶病质患者体质，提高其存活率。

Effects of ω-3 Polyunsaturated Fatty Acids on Colon Cancer

Omega-3 polyunstaurated fatty acids （ω-3PUFA） , mainly derived from fish oils, are essential for the integrity and function of the cells and play a key role as immune response modulators and suppressors of immunologic functions, ω-3PUFA can effectively inhibit the growth and metastasis of colon cancer by inhibiting cell proliferation, promoting cell differentiation, and inducing tumor cell apoptosis by profoundly altering the biochemical make-up of cell membrane lipid composition, regulating the level of lipid metabolism, and modulating the expression of intracelluar genes encoding, ω-3PUFA may also improve the patient＇s immunologic functions and increase the survival rate.