| 移植治疗肝豆状核变性的临床和研究进展 |
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| 引用本文： | 阴瑞红,曲云东,林森. 移植治疗肝豆状核变性的临床和研究进展[J]. 国际消化病杂志, 2007, 27(4): 275-277 |
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| 作者姓名： | 阴瑞红 曲云东 林森 |
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| 作者单位： | 济南市第一人民医院消化内科,250013 |
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| 摘 要： | 肝豆状核变性(WD)是一种遗传性铜代谢障碍性疾病,表现为铜异常沉积而致多脏器损伤.WD致病基因主要在肝脏表达,提供患者正常的肝细胞(或组织)可以纠正其遗传缺陷,改善铜代谢.此文主要从肝移植和细胞移植角度回顾近年来WD治疗的新进展,为进一步治疗WD提出可能的思路和方法.
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| 关 键 词： | 肝豆状核变性 肝移植 细胞移植 |
| 修稿时间： | 2006-06-10 |
Research progression of graft in treatment for wilson disease |
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| YIN Rui-hong,QU Yun-dong,LIN Sen. Research progression of graft in treatment for wilson disease[J]. International Journal of Digestive Disease, 2007, 27(4): 275-277 |
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| Authors: | YIN Rui-hong QU Yun-dong LIN Sen |
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| Affiliation: | Department of Gastroen terology ,the Second Hospital of Shandong University , Jinan(250033 |
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| Abstract: | Wilson disease is a disease with heritage copper dysbolism.Copper that abnormally deposit on organ made liver,brain damaged.Offering normal hepatic cell(or liver organism) can rectification the genetic defect and improve metabolism of copper.The article reviews the therapy advancement of liver transplantation and cellular transplantation in treating wilson disease in order to propose potential treating approach. |
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| Keywords: | Wilson disease Liver transplantation Cellular transplant |
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