葡萄糖酸钙和乳酸钙在大鼠体内的吸收和利用

目的：探讨葡萄糖酸钙和乳酸钙在大鼠体内的吸收和利用。方法：断乳雄性Wistar大鼠50只，随机分成5组，分别用碳酸钙、奶粉钙、葡萄糖酸钙和乳酸钙配制的饲料及基础低钙饲料喂养动物28 d,并分别在第20天和第25天进行3 d食物效价实验及４ d钙代谢实验。 结果：葡萄糖酸钙组大鼠体重增长率为92.1%，钙吸收率及储留率分别为68.2%和85.1%，股骨指数为4.96, 股骨钙存留率为4.6%，各项指标均低于奶粉钙组，高于碳酸钙组(P<0.05或P<0.01)。乳酸钙组大鼠体重增长率为75.1%，钙吸收率及储留率分别为65.5 %和82.0%，股骨指数为4.88，股骨钙储留率为4.1%，优于碳酸钙组（P<0.05或P<0.01），乳酸钙组除体重增长率低于葡萄糖酸钙组外，其他指标与葡萄糖酸钙组比较差异无显著性。 结论：葡萄糖酸钙和乳酸钙均可以作为机体的良好钙源，应用于食品添加剂和药物。

Absorption and utilization of calcium gluconate and calcium lactate in rats in vivo

Objective To study the absorpion and utilization of calcium gluconate and calcium lactate in rats in vivo. Methods Weaning male Wistar rats were randomly divided into 5 groups and fed on CaCO 3, skimmed milk powder, calcium gluconate, calcium lactate, and basic low calcium meal in semi-purified diets, respectively, for 4 weeks. Meanwhile,the experiments of 3 days′ feed efficiency and 4 days′ calcium metabolism were carried out on the 20th and 25th day, respectively. Results In calcium-gluconate group, the incremental rate of body weight,the absorption and retention rate of calcium,the femur index, and retention rate of calcium in femur were 92.1%,68.2%,85.1%,4.96, and 4.6%, respectively, all indexes were lower than those in milk-powder group and higher than those in CaCO 3 group (P<0.05 or P<0.01). The items mentioned above in calcium-lactate group were 75.1%,65.5%,82.0%,4.88 and 4.1%, respectively,also higher than those in CaCO 3 group (P<0.05 or P<0.01),no differences were found between calcium-gluconate group and calcium-lactate group except that the incremental rate of body weight in calcium-lactate group was lower than that in calcium-gluconate group.Conclusion Both calcium gluconate and calcium lactate can be served as the good sources for dietary calcium supplement.