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231例氨基甙类抗生素致聋患者脑干听觉诱发电位分析
引用本文:何恩海,綦宣畅,王洪增,孟兆玮.231例氨基甙类抗生素致聋患者脑干听觉诱发电位分析[J].潍坊医学院学报,2003,25(3):216-217,I001.
作者姓名:何恩海  綦宣畅  王洪增  孟兆玮
作者单位:1. 潍坊医学院耳鼻喉学教研室,山东,潍坊,261042
2. 潍坊医学院附属医院
摘    要:目的 了解氨基甙类抗生素致聋的临床情况。方法 回顾自1980年~2001年收治的231例氨基甙类抗生素致聋患者的临床资料和脑干听觉诱发电位变化。结果 6岁以下患儿112例(48.05%),~14岁87例(38.09%),15岁以上者仅32例(13.86%);全部患者的脑干听觉诱发电位均有不同程度的异常,多数小儿脑干听觉诱发电位明显异常。结论 部分聋儿有明显的残余听力,为言语康复提供依据。

关 键 词:氨基甙类抗生素  脑干听觉诱发电位  耳中毒
文章编号:1004-3101(2003)03-0216-02

The Analysis of Clinical Data about Hearing Loss Caused by Aminoglycosides and ABR in 231 Cases
HE En-hai ,QI Xuan-chang ,WANG Hong-zeng ,MENG Zhao-wei.The Analysis of Clinical Data about Hearing Loss Caused by Aminoglycosides and ABR in 231 Cases[J].Journal of Weifang Medical College,2003,25(3):216-217,I001.
Authors:HE En-hai  QI Xuan-chang  WANG Hong-zeng  MENG Zhao-wei
Institution:HE En-hai 1,QI Xuan-chang 2,WANG Hong-zeng 2,MENG Zhao-wei 2
Abstract:Objective To investigate the clinical data about hearing loss caused by aminoglycosides.Methods Study the clinical data about hearing loss caused by aminoglycosides and auditory brainstem response audiometry (ABR) in 231 cases from 1980 to 2001.Results The deafness rate is 48.05% among 112 cases in the group of individuals under 6 years old,38.09% among 87 cases from 7 to 14 years old,13.86% in 32 cases in the group of individuals ever 15 years old.ABR shows various degree of abnormity.ABR is obviously abnormal among most of children.Conclusion Some of the children have obviously residuary hearing ability which provide evidence for recovering of language.
Keywords:Aminoglycosides  Auditory brainstem response audiometry(ABR)  Totoxicity
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