患儿遗尿与孟鲁司特钠咀嚼片有关

12岁女童患哮喘病,服用孟鲁司特钠咀嚼片5mg,1次/d,同时服用酮替芬1mg,2次/d。2d后出现遗尿,每晚1次,第6天时遗尿增加到每晚3次。停用酮替芬后仍然遗尿。遂停用孟鲁司特钠,1周内无遗尿现象,再次服用该药又出现遗尿,停药后随访4月余,未出现遗尿。

Enuresis induced by montelukast sodium chewable tablets in a child

A 12-year-old girl with asthma was treated with montelukast sodium chewable tablets 5mg once daily and ketotifen 1mg twice daily. Two days later, she presented with enuresis once every night. On day 6, her enuresis was increased to three times at night. She stopped use of ketotifen, but enuresis still occurred. Later, montelukast sodium was discontinued. There was no occurrence of enuresis within a week. The enuresis recurred when she took the drug again. Then she stopped the drug again. At follow-up, 4 months later, there was no recurrence of the enuresis.