| 参附注射液对重度脓毒症患者组织氧代谢的影响 |
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| 引用本文： | 江荣林,雷澍,王灵聪,吴建浓,智屹惠,吴艳春,朱美飞,黄立权,叶雪惠.参附注射液对重度脓毒症患者组织氧代谢的影响[J].中华中医药杂志,2009(7). |
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| 作者姓名： | 江荣林 雷澍 王灵聪 吴建浓 智屹惠 吴艳春 朱美飞 黄立权 叶雪惠 |
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| 作者单位： | 浙江省中医院; |
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| 摘 要： | 目的:观察参附注射液对重度脓毒症患者氧输送的影响。方法:选择ICU收治的52例重度脓毒症患者作为研究对象,随机分为两组,分别给予常规治疗(对照组,25例)和常规+参附注射液治疗(治疗组,27例),观察比较0、6、24、48、72h时两组患者的氧供应(DO2)、氧消耗(VO2)、氧摄取率(ERO2)和乳酸清除率及28d病死率的情况。结果:两组的DO2、VO2、ERO2均较治疗前显著增高或降低(P<0.01),治疗组第6、24、48、72h的DO2、VO2和乳酸清除率均较对照组显著增高(P<0.01),两组的28d病死率则无显著性差异。结论:参附注射液可改善重度脓毒症患者的氧输送,是治疗重度脓毒症的临床有效药物。
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| 关 键 词： | 重度脓毒症 参附注射液 氧输送 |
Effect of Shenfu Injection on tissue oxygen metabolism in patients with severe sepsis |
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| JIANG Rong-lin,LEI Shu,WANG Ling-cong,WU Jian-nong,ZHI Yi-hui,WU Yan-chun,ZHU Mei-fei,HUANG Li-quan,YE Xue-hui.Effect of Shenfu Injection on tissue oxygen metabolism in patients with severe sepsis[J].China Journal of Traditional Chinese Medicine and Pharmacy,2009(7). |
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| Authors: | JIANG Rong-lin LEI Shu WANG Ling-cong WU Jian-nong ZHI Yi-hui WU Yan-chun ZHU Mei-fei HUANG Li-quan YE Xue-hui |
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| Affiliation: | JIANG Rong-lin,LEI Shu,WANG Ling-cong,WU Jian-nong,ZHI Yi-hui,WU Yan-chun,ZHU Mei-fei,HUANG Li-quan,YE Xue-hui(Department of Intensive Care Unit,Zhejiang TCM Hospital,Hangzhou 310006,China) |
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| Abstract: | Objective:To observe the effect of Shenfu Injection on oxygen delivery in patients with severe sepsis.Methods:A total of 52 patients with severe sepsis in ICU were randomly divided into 2 groups:treatment group(n=27) and control group(n=25).The control group 25 cases took routine treatment.The treatment group was given Shenfu Injections plus routine treatment.The parameters of DO2,VO2,ERO2,lactate clearance rate at the beginning and 6h,24h,48h,72h of the trial and 28-day mortality were observed.Results:The ... |
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| Keywords: | Severe sepsis Shenfu Injection Oxygen delivery |
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