Action of hemolysate of polycythemic animals on proliferations of bonne marrow cells

Erythrocytic inhibitor from polycythemic rats depressed mitotic activity of cells of of the erythroid series in mice by 40%. The inhibitory effect lasted about 12 h. The inhibitor acted on the G₂ period. The points of application of the inhibitor were not only blast forms of the erythron but also hematopoietic stem cells.Department of Pathological Physiology, Moscow Medical Stomatological Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR N. A. Fedorov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 3, pp. 337–339, March, 1977.