非小细胞肺癌遗传与表遗传研究若干进展

非小细胞肺癌是恶性肿瘤中导致死亡的主要癌症。非小细胞肺癌早期诊断可及时发现病人,及时治疗,以获得较好的治疗效果。因此,很有必要开发一种能够在癌症早期准确诊断非小细胞肺癌的方法。目前来说,肺癌分子标志物检测在非小细胞肺癌的诊断中有一定的价值。大量分子生物学研究表明,基因多态性是肺癌发生的重要因素。此外,在肺癌发展过程中表遗传改变的重要性也逐渐被认识到。在未来非小细胞肺癌研究中,一种结合流行病学、遗传学和表遗传学的综合的研究方法会显得非常重要。

Some research development on non-small cell lung cancer genetics and genetic expression

Non-small cell lung cancer is the major cancer causing death among the malignant tumors. Early detection non-small cell lung cancer can detect the patients in time and get the treatment in time, to obtain the relative good therapy results. So, it is necessary to develop a method being able to accurately determine the non-small cell lung cancer at the early stage. Currently, the lung cancer marker detection is of certain importance in the non-small cell lung cancer diagnosis. Large volume of molecular biology research demonstrate that gene polymorphism is the important factor of the lung cancer occurrence. Furthermore, the importance of genetic expression changes that occur during lung cancer development has been realized gradually. In the future non-small lung cancer research, a comprehensive method combing epidemiological, genetic and genetic expression research seems very important.