|
|||||
|
|
DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH |
|
| Authors: | Stine H Kresse Magne Skårn Hege O Ohnstad Heidi M Namløs Bodil Bjerkehagen Ola Myklebost Leonardo A Meza-Zepeda |
| Affiliation: | (1) Department of Tumor Biology, Radiumhospitalet, Rikshospitalet, Oslo, Norway;(2) Faculty of Medicine, University of Oslo, Oslo, Norway;(3) Pathology Clinic, Radiumhospitalet, Rikshospitalet, Oslo, Norway;(4) Norwegian Microarray Consortium, Department of Molecular Biosciences, University of Oslo, Oslo, Norway |
| Abstract: | BackgroundMalignant peripheral nerve sheath tumors (MPNSTs) are rare and highly aggressive soft tissue tumors showing complex chromosomal aberrations. In order to identify recurrent chromosomal regions of gain and loss, and thereby novel gene targets of potential importance for MPNST development and/or progression, we have analyzed DNA copy number changes in seven high-grade MPNSTs using microarray-based comparative genomic hybridization (array CGH). |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |