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比较牡丹皮炒炭前后的化学成分变化
引用本文:李娴,卫向龙,赵学龙,丁安伟. 比较牡丹皮炒炭前后的化学成分变化[J]. 中国实验方剂学杂志, 2011, 17(23): 32-35
作者姓名:李娴  卫向龙  赵学龙  丁安伟
作者单位:1. 河南中医学院,郑州,450008
2. 南京市中医院,南京,210001
3. 南京中医药大学江苏省方剂研究重点实验室,南京,210046
基金项目:国家"十一五"科技攻关项目(2006BAI09B006-02);2008年江苏省研究生培养创新工程(CX08B_200Z)
摘    要:目的:研究牡丹皮炒炭前后化学成分的变化。方法:采用高效液相色谱法,对牡丹皮炒炭前后有变化的成分进行初步的定性定量研究。结果:没食子酸和5-羟甲基糠醛含量随炒制时间和炒制温度的增加而增加,但当增加一定程度后开始降低;黄酮类成分槲皮素、山奈素、异鼠李素等含量下降。结论:通过分析牡丹皮炒炭前后各种化学成分的变化,为进一步研究丹皮炭的止血机制提供一定的依据。

关 键 词:丹皮炭  化学成分  高效液相
收稿时间:2010-10-19

Compared before and after the Chemical Compositionof Carbon Cortex Moutan Study of Changes
LI Xian,WEI Xiang-long,ZHAO Xue-long and DING An-wei. Compared before and after the Chemical Compositionof Carbon Cortex Moutan Study of Changes[J]. China Journal of Experimental Traditional Medical Formulae, 2011, 17(23): 32-35
Authors:LI Xian  WEI Xiang-long  ZHAO Xue-long  DING An-wei
Affiliation:Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China;Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China;ZHEJIANG A & F UNIVERSITY, Hangzhou 311300, China;Nanjing University of Traditional Chinese Medicine, Key Laboratory for Modern Research of Traditional Chinese Medical Formulae of Jiangsu, Nanjing 210046, China
Abstract:Objective: Study cortex moutan and carbonized cortex moutan determination of chemical composition. Method: High performance liquid chromatography, on carbonized cortex moutan changes before and after a preliminary qualitative and quantitative composition of. Result: Gallic acid and 5-HMF content increased with frying time and frying temperature increased, but decreased after an increase to a certain extent, flavonoids quercetin, kaempferol, isorhamnetin, etc. decreased. Conclusion: By analyzing the carbonized cortex moutan changes before and after the various chemical components, carbonized cortex moutan for further study of the hemostatic mechanism paeonol provide some basis.
Keywords:carbonized cortex moutan  chemical composition  HPLC
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