| 鱼鳔丸质量标准的研究 |
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| 引用本文： | 刘燕,郑笑为,汪琪,鲁静. 鱼鳔丸质量标准的研究[J]. 中国药事, 2009, 23(8): 793-795 |
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| 作者姓名： | 刘燕 郑笑为 汪琪 鲁静 |
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| 作者单位： | 中国药品生物制品检定所,北京,100050 |
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| 基金项目： | 国家药品标准提高行动计划 |
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| 摘 要： | 目的建立鱼鳔丸中当归、五味子、肉苁蓉的薄层鉴别方法及山茱萸中马钱苷的高效液相含量测定方法。方法采用Agilent TC-C18色谱柱；流动相为乙腈-水（12：88）；流速为1．0mL·min^-1；检测波长240nm；柱温25℃。结果马钱苷在0．1632-1．632μg范围内呈良好的线性关系，r=0．9999，平均回收率98．1％，RSD为0．58％（n=6）。结论该方法操作简便，重复性好，结果准确可靠，适用于该药的质量控制。
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| 关 键 词： | HPLC 鱼鳔丸 马钱苷 |
Study on the Establishment of the Quality Standard of Yubiao Pills |
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| Liu Yan,Zheng Xiaowei,Wang Qi,Lu Jing. Study on the Establishment of the Quality Standard of Yubiao Pills[J]. Chinese Pharmaceutical Affairs, 2009, 23(8): 793-795 |
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| Authors: | Liu Yan Zheng Xiaowei Wang Qi Lu Jing |
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| Affiliation: | (National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050) |
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| Abstract: | Objective To identify Angelica. , Fructus Schisandrae and Herba Cistanches by TLC meth od and to determine Loganin in Yubiao Pills by HPLC method. Methods Using a Agilent C18 column, a mixture of acetonitrile-water （12 ： 88） was mobile phase, the detetive wavelenth was set at 240nm and the column temperature was 25℃. Results The linear range of Loganin was from 0. 1632mg to 1. 632mg （r= 0. 9999）. The average recoverage was 98. 1% with RSD as 0.58%（n= 6）. Conclusions The method is simple, accurate and reliable, and it can be used in the quality control of crude drug. |
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| Keywords: | HPLC |
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