A clinically significant interaction between ciprofloxacin and theophylline |
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| Authors: | A. H. Thomson G. D. Thomson M. Hepburn B. Whiting |
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| Affiliation: | (1) Department of Materia Medica, University of Glasgow, Glasgow, UK;(2) Department of Pharmacy, Stobhill General Hospital, Glasgow, UK |
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| Abstract: | Summary We report a case of theophylline toxicity following the co-administration of ciprofloxacin. Total theophylline clearance fell from 2.3 l·h–1 to 0.8 l·h–1 when ciprofloxacin was added to the treatment regimen and returned to 2.1 l·h–1 after ciprofloxacin was discontinued. |
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| Keywords: | theophylline ciprofloxacin drug interaction |
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