| 不同流行区流行性出血热病人血清电泳分析 |
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| 引用本文： | 张云,窦蕊,叶炳辉,赵学忠,朱小龙,朱昌亮,吴光华.不同流行区流行性出血热病人血清电泳分析[J].南京医科大学学报,1989(4). |
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| 作者姓名： | 张云 窦蕊 叶炳辉 赵学忠 朱小龙 朱昌亮 吴光华 |
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| 作者单位： | 南京军区军事医学研究所，南京军区军事医学研究所，南京医学院寄生虫学教研室，南京军区军事医学研究所，南京军区军事医学研究所，南京医学院寄生虫学教研室，南京军区军事医学研究所 |
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| 摘 要： | 用等电聚焦电泳分析流行性出血热(EHF)血清,发现EHF R_(22)毒株免疫兔血清和家鼠型EHF病人血清中有一特异的等电点(pI4.9蛋白),而30例野鼠型EHF病人血清,EHF陈株病毒免疫兔血清以及50份正常人血清皆没有此种蛋白,但部分肝炎病人和红斑狼疮病人血清中亦有p14.9蛋白,表明p14.9蛋白不是家鼠型EHF病人特有,若仅对EHF血清而言,pI4.9蛋白可能是抗家鼠型EHF病毒成份。
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| 关 键 词： | 出血热 流行性 血浆 等电聚焦 人类 |
PRELIMINARY STUDY ON SERA OF PATIENTS WITH EPIDEMIC HEMORRHAGIC FEVER OF DIFFERENT ENDEMIC AREAS BY ISOELECTRIC FOCUSING |
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| Zhang Yun,et al..PRELIMINARY STUDY ON SERA OF PATIENTS WITH EPIDEMIC HEMORRHAGIC FEVER OF DIFFERENT ENDEMIC AREAS BY ISOELECTRIC FOCUSING[J].Acta Universitatis Medicinalis Nanjing,1989(4). |
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| Authors: | Zhang Yun |
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| Abstract: | Sera of EHF were analysed by isoelectric focusing.A special protein with pI 4.9 was found in the serum of rabbit immunized by R_(22) virus strain and serum of patients with epidemic hemorrhagic fever(EHF)of domestic rodent type,it was absent in 30 sera of patients with EHF of field rodent type,sera of rabbit immunized by Chen virus strain and 50 sera of normal persons examined.Some sera of patients with hepatitis or dermatopathy had this pI 4.9 protien too.These results indicate that pI 4.9 protien is not specific for sera of EHF of domestic rodent type. If comparison is only within sera of EHF,the protein with pI 4.9 seems to be a component only against virus of EHF of domestic rodent type. |
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| Keywords: | hemorrhagic fever epidcmic plasma isoelectric focusine human |
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