同时多原发大肠癌与大肠腺瘤

目的 探讨大肠同时多原发癌的发病情况及其与大肠腺瘤的关系.方法 连续观察可切除并经病理证实的大肠癌166例.结果 发现同时多原发大肠癌8例(4.8%),单发癌有42例合并腺瘤(27.7%),同时癌有4例合并腺瘤(50%),4例合并腺瘤的同时癌共有腺瘤14处,其中2例3处腺瘤癌变,癌变率为伴腺瘤的50%.全组18个癌灶中8个小于3cm.结论 大肠同时多原发癌并非罕见,且与腺瘤癌变有关.全结肠镜检查是提高诊断率的重要手段.

SYNCHRONOUS MULTIPLE PRIMARY CANCER AND ADENOMA OF LARGE INTESTINES

PURPOSE To discuss induction and relation of synchronous multiple primary cancer to adenoma of large intestines. METHODS Continuous observation of resectable and pathologically proved cancer of large intestines of 166 cases. RESULTS We discovered 8 cases (4. 8%) of synchronous multiple primary cancer of large interstines. 43 cases of single primary cancer of concomitant adenoma (27. 7%). The 4 cases of synchronous cancer had merged adenoma (50%). The 4 cases of synchronous cancer had concomitant adenoma of 14 sites. Of these 2 cases had neoplastic change in 3 sites. The rate of neoplastic change was 50% concomitant adenoma. In the whole group, of the 18 cancer sites, 8 nidi were less than 3cm. CONCLUSION Synchronous cancer of large intestines is not rare, and is related to malignant change of adenomas. complete colonoscopy is an important means to improve diagnostic rate.