56例2型糖尿病的治疗效果分析

目的 探讨甘精胰岛素联合口服降糖药治疗2型糖尿病的临床效果.方法 选取2011年1月～2012年1月到本院门诊治疗的口服降糖药控制血糖不佳的2型糖尿病患者56例.所有患者在饮食控制及生活方式调节的基础上,应用甘精胰岛素联合口服降糖药治疗,连续治疗3个月,检测治疗前后空腹血糖（FBG）、餐后2h血糖（2hBG）、糖化血红蛋白（HbA1c）、空腹C肽（FCP）、餐后2hC肽（2hCP）、质量指数（BMI）、尿糖（GLU）水平的变化.结果 所有患者均顺利完成实验,全部患者的FBG、2hBG、HbA1c、FCP、2hCP、BMI、GLU在治疗3个月后均有显著改善（P＜0.05）.结论 甘精胰岛素联合口服降糖药治疗2型糖尿病疗效好,对于2型糖尿病患者具有重要意义,值得临床推广应用.

Curative effect analysis of 56 patients with type 2 diabetes

Objective To investigate the effect of insulin glargine combined with oral hypoglycemic drugs for type 2 diabetes.Methods 56 patients with type 2 diabetes treated in outpatient department of our hospital for poor control of blood-glucose by oral hypoglycemic drugs from January 2011 to January 2012 were selected.All patients were continu- ously treated by insulin glargine combined with oral hypoglycemic drugs for 3 months,on the basis of diet control and lifestyle adjustment.The fasting blood-glucose （FBG）,2 hours postprandial blood-glucose （2hBG）,glycosylated hemoglobin （HbAlc）,fasting C-peptide （FCP）,2 hcmrs postprandial C-peptide （2hCP）,body mass index （BMI）,glucose in urine （GLU） were detected before and after treatment.Results All patients smoothly went through trial.Three months after treatment,the FBG,2hBG,HbAlc,FCP,2hCP,BMI,GLU of all patients were significantly improved （P〈0.05）.Conclusion For type 2 diabetes,insulin glargine combined with oral hypoglycemic drugs has good curative effect and important significance for patients,and is worth clinical promotion.