重型颅脑外伤患者早期肠内营养的临床价值

目的 探讨早期肠内营养治疗对重型颅脑外伤患者的临床价值.方法 选取本院行早期肠内营养干预治疗的重型颅脑外伤患者34例为观察组,同期行普通营养干预的重型颅脑外伤患者33例为对照组;从营养状态、并发症发生情况、预后免疫功能方面对比分析两组的治疗效果.结果 治疗前两者患者总蛋白（TP）和清蛋白（ALB）含量差异无统计学意义;治疗后两组TP和ALB水平均有所升高,且观察组平均水平显著高于对照组（P＜0.05）;观察组并发症显著少于对照组（P＜0.05）;观察组IgM、IgG水平显著高于对照组（P＜0.05）,IgA水平与对照组差异无统计学意义（P＞o.05）,CRP水平显著低于对照组（P＜0.05）.结论 早期肠内营养治疗重型颅脑外伤起效快,效果好,可显著改善患者体质,减少并发症发生,值得临床推广.

Clinical study of early enteral nutrition on patients with severe craniocerebral trauma

Objective To discuss the clinical effect and prognosis of early enteral nutrition on patients with severe craniocerebral trauma. Methods 34 patients with severe craniocerebral trauma treated by early enteral nutrition for intervention were selected as observation group,while other 33 patients with severe craniocerebral trauma intervened by general nutrition during the corresponding period were chosen as control group. The nutritional status,occurrence of complication,and immune function in prognosis in both groups were comparatively analyzed. Results There was no sig nificant difference in content of total protein （TP） or albumin （ALB） before treatment in the two groups. After therapy, two indexes in both groups improved and the average levels of these two indexes in the observation group were remarkably higher than those in the control group （P〈0.05）. The occurrence of complications in the observation group was obviously less than that in the control group （P〈0.05）. Compared with control group,the values of immunoglobulin m （IgM） and immunoglobulin G （IgG） were much higher in the observation group （P〈0.05）,no significant difference displayed in immunoglobulin A （IgA） （P〉0.05）,and the level of C-reactive protein was greatly lower in observation group （P〈0.05）. Conclusion Early enteral nutrition in the treatment of severe craniocerebral trauma can obtain a fast and favorable effect,remarkably improve patient＇s constitution,and reduce the incidence of complications,which is worthy of expansion in clinic.