全胸腔镜肺叶切除与开胸肺叶切除治疗非小细胞肺癌的对比研究

目的探讨全胸腔镜肺叶切除与开胸肺叶切除治疗非小细胞肺癌的效果。方法选取2010年5月～2012年5月在本院进行治疗的非小细胞肺癌患者85例,随机分为胸腔镜组43例和开胸组42例，胸腔镜组采用全胸腔镜肺叶切除术，开胸组采用开胸肺叶切除术。观察两组平均手术时间、术中出血量、术后胸腔引流量、住院天数及术后并发症发生情况，采用视觉模拟评分（VAS）评估术后疼痛程度，并观察两组并发症发生率。结果胸腔镜组术中出血量、术后胸腔引流量及住院天数皆少于开胸组（P〈0．05）。手术时间显著长于开胸组（P〈0．05）。胸腔镜组VAS显著低于开胸组（P〈0．05）。胸腔镜组并发症发生率为11．63％，开胸组为38．10％，两组比较差异有统计学意义（P〈0．05）。结论全胸腔镜肺叶切除术治疗非小细胞肺癌较为安全、可靠，值得临床推广应用。

Comparative study on complete video-assisted thoracic surgery and tho- racotomy lobectomy in the treatment of non-small cell lung cancer

Objective To explore the curative effect of complete video-assisted thoracic surgery and thoracotomy lobectomy in the treatment of non-small cell lung cancer.Methods 85 cases of patients with non-small cell lung can- cer were collected from May 2010 to May 2012 in our hospital,who were randomly divided into the thoracoscopic group 43 cases and thoracotomy group 42 cases, completely video-assisted thoracoscopic lobectomy was used to thora- coscopic group,conventional thoracotomy was used to thoracotomy group.The average operation time,bleeding volume, postoperative drainage volume,hospitalization days and postoperative complications,degree of pain which was evaluated by VAS after operation,and incidence of complications of the two groups were all observed.Results The bleeding vol- ume,postoperative drainage volume and length of hospital stay of the thoracoscopic group was less than that of the tho- racotomy group,the difference was significant （P〈0.05）,and the operation time was significantly longer,the difference was significant （P〈0.05）.The postoperative VAS of the thoracoscopic group was significantly lower than that of the tho- racotomy group （P〈0.05）.The incidence of complications of the thoracoscopic group was 11.63%,while that of the tho- racotomy group was 38.10%,the difference was significant between the two groups （P〈0.05）.Conclusion Complete video-assisted thoracic surgery for non-small cell lung cancer is safe,reliable,and worthy of clinical application.