血尿酸浓度水平与急性脑梗死颈动脉粥样斑块的关系研究

目的 研究血尿酸浓度水平与急性脑梗死颈动脉粥样斑块的相关性,以探讨脑梗死的危险因素,从而为临床诊治及预防提供重要参考.方法 抽取2012年9月～2013年9月本院收治的急性脑梗死患者,根据入选标准选择脑梗死患者70例,根据是否存在颈动脉粥硬化斑块分为动脉粥样硬化血栓形成组（A组）和非动脉粥样硬化血栓形成组（B组）,每组各35例,正常对照组35例来源于同期健康体检者.检测3组患者的血尿酸浓度,对比分析各组患者的检测结果.结果 A、B组患者血尿酸水平较对照组发生显著升高（P＜0.05）,且A组检测结果较B组高（P＜0.05）;A组中不稳定性斑块的血尿酸水平较稳定性斑块患者高（P＜0.05）.结论 血尿酸水平在不同脑梗死及不同斑块患者中检测结果存在较大差异,对临床诊断、治疗方案的选择、斑块类型判断、预后评估等均具有重要的临床意义.

Relationships research of blood uric acid level and carotid atherosclerotic plaque in acute cerebral infarction

Objective To explore the risk factors of cerebral infarction by correlational study of blood uric acid （BUA） level and carotid atherosclerotic plaque in acute cerebral infarction, and provide important references for clinical diagnosis and prevention. Methods 70 patients with cerebral infarction meeting the criteria admitted into our hospital from September 2012 to September 2013 were selected and they were evenly divided into atherosclerotic thrombosis group （group A） and non-atherosclerotic thrombosis group （group B） based on whether there was carotid atherosclerotie plaque.35 healthy participants after physical examinations during the same period were selected as normal control group.The BUA level among these three groups were tested and comparatively analyzed. Results The BUA levels in group A and group B remarkably increased in comparison with that in the control group （P〈0.05）,and the testing value in the group A was higher than that in the group B （P〈0.05）.In group A,the BUA level from unstable plaque was high- er than that from the stable plaque （P〈0.05）. Conclusion There are large differences in testing outcomes of BUA levels in patients with varied types of cerebral infarction and plaques,which all play important clinical significance in diagnosis,selection of therapeutic regimen,judgment of plaque type,and prognosis evaluation.