老年代谢综合征患者动脉弹性变化分析及护理对策

目的 探讨老年代谢综合征患者动脉弹性功能变化情况及其影响因素.方法 对221例老年代谢综合征患者(实验组)采用CVProfilorDO-2020系统进行了大动脉弹性(C1)和小动脉弹性(C2)的检测,并与206例老年健康者(对照组)的相应检测值进行了比较,分析大小动脉弹性与收缩压(SBp)、舒张压(DBp)、平均压(MBp)、脉压(Pp)、体重指数(BMI)、体脂含量、血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和空腹血糖(FBG)等指标的相关性.结果 (1)与对照组比较,实验组C1和C2明显降低,SBp、DBp、MBp、Pp、BMI和体脂均明显升高.(2)与对照组比较,实验组的血清TC、TG、LDL-C和FBG水平明显升高,而HDL-C明显降低.(3)C1、C2与年龄、SBp、DBp、MBp、Pp以及血清TC、LDL-C、FBG浓度呈显著的负相关,但与体重指数呈正相关,与体脂、血清TG浓度及血清HDL-C浓度无明显的相关性.C1与C2之间呈显著的正相关.结论 老年代谢综合征患者的动脉弹性明显降低,动脉弹性功能检测为临床评价血管结构和功能损害及其危险分层提供了一种替代方法.

Analysis in changes of arterial elasticity in elderly patients with metabolic syndrome and nursing countermeasures

Objective The present study was performed to evaluate changes of arterial elasticity in elderly patients with metabolic syndrome and its influence factors. Methods Using modified Windkessel model of the circulation and pulse waveform analysis,large artery elasticity indices(C1) and small artery elasticity indices (C2) of 221 old metabolic syndrome patients(the experimental group) and 206 old healthy subjects (the control group) were measured. Correlation of arterial elasticity changes with systolic blood pressure (SBp), diastolic blood pressure (DBp), mean blood pressure (MBp),pulse pressure (Pp), body weight indexes(BMI),body adipic weight, level of serum total cholesterol(TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and glucose was also analyzed. Results C1 and C2 reduced in the experimental, but SBp, DBp, MBp, Pp, BMI, body adipic weight, level of serum total cholesterol ( TC ), triglyceride (TG), low density lipoprotein cholesterol (LDL-C)and glucose were higher. There was a negative association between C1 and C2 and age, SBp, DBp, MBp and Pp and positive correlation with body weight indexes. But C1 and C2 were not correlated with body adipic weight, TG and HDL-C. Conclusions Arterial elasticity of elderly patients with metabolic syndrome were reduced. Arterial elasticity assessment offers a means of risk stratification for the clinical evaluation of vascular structural and functional injuries.