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血清肌红蛋白放射免疫测定早期诊断急性心肌梗塞的意义
引用本文:管淑良,米世簪,赵华月,田大武,李美颖.血清肌红蛋白放射免疫测定早期诊断急性心肌梗塞的意义[J].华中科技大学学报(医学版),1988(2).
作者姓名:管淑良  米世簪  赵华月  田大武  李美颖
作者单位:同济医科大学附属同济医院内科心血管组 (管淑良,米世簪,赵华月),同济医科大学附属同济医院同位素室 (田大武),同济医科大学附属同济医院同位素室(李美颖)
摘    要:应用放射免疫(RIA)测定分析血清肌红蛋白(Mb)浓度,早期诊断心肌梗塞(AMI)。结果表明AMI早期血清Mb浓度超过正常水平的4.7倍;在其他血清酶升高前一天,就可观察到69.9%的AMI忠者血清Mb浓度升高。血清Mb浓度的峰值与心肌损伤范围的大小,严重痖状的有无以及预后的好坏有直接关系,与心电图ST段抬高的幅度呈正相关。

关 键 词:肌红蛋白  急性心肌梗塞  放射免疫测定

A Study of Early Diagnosis of Acute Myocardial Infarction with Radioimmunoassay of Serum Myoglobin
Guan Shuliang,Mi Shizan,Zhao Huayue Cardiovascular Group.A Study of Early Diagnosis of Acute Myocardial Infarction with Radioimmunoassay of Serum Myoglobin[J].Journal of Huazhong University of Science and Technology(Health Sciences),1988(2).
Authors:Guan Shuliang  Mi Shizan  Zhao Huayue Cardiovascular Group
Institution:Guan Shuliang,Mi Shizan,Zhao Huayue Cardiovascular Group,Department of Internal Medicine,Tongji Hospital,Tongji Medical University,WuhanTian Dawu,Li MeiyingIsotopic Laboratory,Tongji Hospital,Tongji Medical University,Wuhan
Abstract:The present arttcle reported on the significance of the serum myo-globin (Mb) concentration measured with radioimmunoassay (RIA) in early diagnosis of acute myocardial infarction (AMI). The results showed that at the early stage of AMI, the concentration of serum Mb increased considerably, amounting to 4.7 times higher than the normal level. The increase of serum Mb concentrattion was observed in 69.9% of AMI cases one day earlier than that of other serum enzymes. Furthermore, the peak level of serum Mb was directly correlated with size of myocardial injury, the occurrence of complications, and the prognosis of myocardial . infarction, and it had a positive correlation with the elevation of ST segment in ECG.
Keywords:myoglobin  acute myocardial infarction  radioimmunoassay
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