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早产儿视网膜病发病情况及危险因素分析
引用本文:张欣,王颖,陈宜,郭在晨,黎晓新. 早产儿视网膜病发病情况及危险因素分析[J]. 中国实用儿科杂志, 2007, 22(9): 660-662
作者姓名:张欣  王颖  陈宜  郭在晨  黎晓新
作者单位:1. 北京大学第一医院儿科,北京,100034
2. 北京大学人民医院眼科,北京,100034
摘    要:目的探讨早产儿视网膜病(ROP)发病情况及影响ROP患病的危险因素。方法对2004-03—2005-12在北京大学第一医院新生儿监护室住院的胎龄≤34周和(或)出生体重≤2000g的早产儿在生后4~6周或校正胎龄至32周时进行眼底检查,并对相关危险因素进行分析。结果203例早产儿中有25例发生ROP,发生率为12.31%,7例出现阈值或阈值前病变需要治疗,占3.44%,Logistic回归分析表明小胎龄、低出生体重、母亲合并妊娠期糖尿病是发生ROP的危险因素,ROP组与正常眼底组在这三方面差异均有统计学意义(P<0.05)。结论小胎龄、低出生体重、母亲合并妊娠期糖尿病是发生ROP的危险因素。

关 键 词:视网膜病  早产儿 低出生体重
文章编号:1005-2224(2007)09-0660-03
修稿时间:2007-02-15

Incidence and risk factor analysis of retinopathy of premature infants
ZHANG Xin,WANG Ying,CHEN Yi,et al.. Incidence and risk factor analysis of retinopathy of premature infants[J]. Chinese Journal of Practical Pediatrics, 2007, 22(9): 660-662
Authors:ZHANG Xin  WANG Ying  CHEN Yi  et al.
Affiliation:ZHANG Xin,WANG Ying,CHEN Yi,et al.Department of intensive care unit,Peking University First Hospital.Beijing,100034 China
Abstract:Objective This study was designed to learn the incidence of ROP and the risk factors associated with the development of ROP.Methods From March 2004 till December 2005,203 premature infants in NICU of the First Hospital of Peking University with birth weight less than 2000g or gestational age(GA)less than 34 weeks underwent ophthalmologic examination 4~6 weeks after their birth.Results In 203 premature infants,the incidence of ROP was 12.31%.Seven cases(3.44%) developed threshold or prethreshold ROP.Logistic regression analysis indicated that young gestational age,low birth weight and infant of diabetic mother were associated with the development of ROP.Conclusion Young gestational age,low birth weight and infant of diabetic mother are the risk factors for the development of ROP.
Keywords:Retinopathy  Premature  Low birth weight
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