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发射计算机断层脑血流显像在儿童癫癎诊断的应用
引用本文:张遵城,郑妙瑢,李小东,董萍,孙慧东.发射计算机断层脑血流显像在儿童癫癎诊断的应用[J].天津医药,1998(9).
作者姓名:张遵城  郑妙瑢  李小东  董萍  孙慧东
作者单位:天津医科大学第二医院核医学科 300211(张遵城,郑妙瑢,李小东,董萍),天津医科大学第二医院核医学科 300211(孙慧东)
摘    要:对127例癫痫儿童于癫痫发作间歇期进行单光子发射计算机断层(SPECT)脑血流显像,并与脑电图(EEG)、脑CT和MRI检查进行比较。结果表明,SPECT脑血流显像阳性率高达82.7%,EEG、脑CT和MRI的阳性率分别为50.4%,18.4%和32.1%。EEG出现异常时,SPECT脑血流显像常亦有异常,二者定位结果的一致及相对一致率为78.1%(25/32)。脑CT出现局灶性异常时,SPECT脑血流显像亦会有相应部位的异常。说明SPECT脑血流显像在癫痫灶的检出和定位诊断上有一定价值。

关 键 词:单光子发射计算机断层  脑血流显像  儿童癫癎

Clinical Application of SPECT Cerebral Blood Flow Imaging in Diagnosing Childhood Epilepsy
Zhang Zuncheng,Zheng Miaorong,Li Xiaodong,et al.Clinical Application of SPECT Cerebral Blood Flow Imaging in Diagnosing Childhood Epilepsy[J].Tianjin Medical Journal,1998(9).
Authors:Zhang Zuncheng  Zheng Miaorong  Li Xiaodong  
Institution:Zhang Zuncheng,Zheng Miaorong,Li Xiaodong,et al Department of Nuclear Medicine,The Second Hospital of Tianjin Medical University 300211
Abstract:SPECT cerebral blood flow imagings were performed on 127 epileptic children during intermission and were compared with electroencephalogram(EEG) , X-ray CT and MRI. The results indicated that the highest positive rate(82.7%)was found in SPECT,the positive rate of EEG.CT and MRI was 50.4%, 18.4% and 32.1% respectively. When EEG showed abnormality, the SPECT might show abnormality too. The localization of epileptic foci with EEG was in complete or relative concordance with SPECT in 25/32(78.1 % )patients. If CT scan showed a focal abnormality, the local abnormal finding was also found in SPECT. Thereby it was suggested that SPECT cerebral blood flow imaging may be valuable in detecting and localizing epileptic foci.
Keywords:single photon emission computed tomography( SPECT) cerebral blood flow imaging childhood epilepsy
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