| 血清酶测定在恶性肿瘤诊断中的应用 |
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| 引用本文： | 程佩萍,宫继勇,张凡,陈建文.血清酶测定在恶性肿瘤诊断中的应用[J].实用全科医学,2008,6(7):743-744. |
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| 作者姓名： | 程佩萍 宫继勇 张凡 陈建文 |
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| 作者单位： | 安徽省蚌埠医学院第一附属医院检验科,233004 |
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| 摘 要： | 目的探讨3种血清酶活性联合检测对诊断和鉴别恶性肿瘤的应用价值。方法应用速率法检测121例恶性肿瘤患者血清γ-谷氨酰转移酶（GGT）、乳酸脱氢酶（LDH）、碱性磷酸酶（ALP）3种血清酶。结果3种血清酶联合检测其平均阳性率以肝癌最高为66．0％，其次胃癌组43．3％，直肠癌组39．0％，肺癌组34．7％，与正常对照组比较差异有统计学意义（P〈0．01）。结论3种血清酶活性联合检测，提高了临床检测肿瘤的敏感性、有效性。在疗效监测方面可为临床提供有价值的资料。
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| 关 键 词： | 血清酶 恶性 肿瘤 |
Application of Serum Enzyme Determination for Diagnosis of Malignant Tumor |
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| Institution: | CHENG Pei-ping, GONG Ji-yong, ZHANG Fan, et al. (Department of Clinical Medical Laboratory, the Affiliated Hospital of Bengbu Medical College, Anhui 233004, China) |
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| Abstract: | Objective To study the value of three serum enzymes determination for diagnosis and identification of malignant tumor. Methods Serum of 121 malignant tumor patients was examined for γ-glutamyltransferase（ GGT）. lactate dehydrogenase （ LDH ） and alkaline phosphatase（ALP） by enzymatic kinetic assay, Results The positive rates of three serum enzymes were respectively 66, 00% for hepatoma,43,33% for gastric cancer,39.00% for rectal cancer and 34.66% for lung cancer, and these differences were statistics significance compared with the control（ P 〈 0. 01 ）, Conclusions Three serum enzymes determination increases the sensitivity and effectivity of diagnosis for malignant tumor in clinical practice and provide some valuable information about their therapeutic effect, |
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| Keywords: | Enzyme Malignant Tumor |
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