中波高能紫外光治疗白癜风疗效与影响因素分析

目的：评价中波高能紫外光治疗白癜风的临床疗效及其影响因素.方法：采用美国DuaLightTMUV120-2型高能紫外光治疗仪治疗85例白癜风患者,共211处皮损.治疗前判定皮肤类型,测定最小红斑量.照射起始剂量为最小红斑量的2倍,逐渐增加照射剂量,每周照射1～2次,规律治疗3个月后判定疗效.结果：皮损的有效率为93.36％,痊愈率为52.61％.疗效影响因素分析显示年龄、不同部位、病程以及照射频率对治疗效果有显著影响.结论：中波高能紫外光治疗白癜风疗效高、副作用少.

Efficacy and influencing factors of targeted UVB in the treatment of vitiligo

Objective To assess the efficacy and influencing factors of targeted UVB in the treatment of vitiligo. Methods Two hundred and eleven lesions of 85 patients with vitiligo were treated with targeted UVB,one to two times per week,with DualightTM UV 120-2 targeted phototherapy system （Theralight Inc. USA）. The skin type and the minimal erythema dose （MED） were measured before treatment. The initial dosage was 2 times of MED,and the dosage was gradually increased. The efficacy and safety were evaluated 3 months later. Results The total efficacy and cure rate were 93.36% and 52.61%, respectively. The site of the lesion, age,duration,of the disease and the lesion size were positively correlated to the therapeutic effects （P〈O.01）. Conclusion Targeted UVB is safe and effective in treating vitiligo.