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天然型无机骨修复良性溶骨性骨缺损的临床观察
引用本文:李鼎锋,戴景蕊,马贵骧.天然型无机骨修复良性溶骨性骨缺损的临床观察[J].中国修复重建外科杂志,1998,12(4):220-222.
作者姓名:李鼎锋  戴景蕊  马贵骧
作者单位:1. 中国医学科学院中国协和医科大学肿瘤医院骨瘤科,北京,100021
2. 中国医学科学院中国协和医科大学肿瘤医院诊断科,北京,100021
3. 北京积水潭医院骨科研究所
摘    要:为寻找良性骨缺损理想的充填材料,特别是修复儿童良性溶骨性较大的骨缺损,采用天然型无机骨(NNB)充填良性溶骨性骨缺损5例,其中骨囊肿3例,纤维异样增殖症1例,非骨化性纤维瘤1例。病变位于股骨中上段1例,股骨下段3例,肱骨上段1例。5例均行病灶开窗刮除,彻底清除内膜及瘤样病变。充填方块状NNB,术后伤口均Ⅰ期愈合。术后3个月~6个月活动正常。术后X线片复查见方块状NNB间及其内的间隙影消失,新生骨与周围骨壳融合,显示病灶愈合。经7个月~2年随访,病变区无复发。认为,NNB是修复良性溶骨性骨缺损理想的充填材料。

关 键 词:天然型无机骨  良性骨肿瘤  骨缺损

LINICAL OBSERVATION ON BENIGN OSTEOLYTIC BONE DEFECTS TREATED WITH NATURAL NON-ORGANIC BONE
Li Dingfeng,Dai Jingrui,Ma Guixiang.LINICAL OBSERVATION ON BENIGN OSTEOLYTIC BONE DEFECTS TREATED WITH NATURAL NON-ORGANIC BONE[J].Chinese Journal of Reparative and Reconstructive Surgery,1998,12(4):220-222.
Authors:Li Dingfeng  Dai Jingrui  Ma Guixiang
Institution:Department of Bone Tumor, Cancer Institute of Chinese Academy of Medical Sciences, Beijing, P.R. China.
Abstract:It is extremely necessary to find an ideal filling material for the treatment of benign bone defect, particularly those benign osteolytic defect in children with a comparatively large cavity. From July, 1995 to December, 1996, 10 cases of benign osteolytic bone defects were treated, in which 5 cases of benign osteolytic defects, 3 cases of bone cysts, 1 case of fibrous dysplasia of bone and 1 case of non-ossifying fibroma. After through curettage of the cavity, the natural non-organic bone in cube-shaped was used to fill the prepared cavity. The results showed that the activities of the patients resumed normal in 3 to 6 months after operation. The roentgenographic examination after operation showed that the lucent spaces between NNB cubes disappeared with obvious new bone formation and the bony cavity was obliterated with newly-formed bone. There was no recurrence of the lesion during a follow-up of 7 to 24 months. It was concluded that to treat the osteolytic defect of bone with NNB was a method of choice. The new bone formation appeared early in large amount and increased rapidly.
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