泉州地区肝炎患者TTV感染状况调查

「目的」了解泉州地区各型肝炎患者ＴＴＶ感染情况。「方法」设计特异性引物采用巢式ＰＣＲ方法对５７例肝炎患者及２０例健康献血员的血清标本进行ＴＴＶＤＮＡ检测。「结果」肝炎患者ＴＴＶＤＮＡ阳性率为１５．８％，其中乙型肝炎（或重叠丁型肝炎）患者ＴＴＶＤＮＡ阳性率为２５．０％（６／２４），非Ａ－Ｇ型肝炎患者ＴＴＶＤＮＡ阳性率为１３．６４％（３／２２），甲、戊型肝炎患者未检出；健康献血员为３５．０％。ＴＴＶＤ

Infection Status of Transfusion Transmitted Virus (TTV) in Hepatitis Patients in Quanzhou Area

Objective] To investigate the infection status of transfusion transmitted virus (TTV) infection among hepatitis patients in Quanzhou area. [Methods] TTVDNA from sera of 57 hepatitis patients and 20 blood donors were detected by nested polymerase chain reaction (nested PCR) with specific primers. [Results] TTVDNA was detected in sera from 9 hepatitis patients among 6 patients with HVB HDV, 3 with non A G and 7 blood donors. Among 9 TTV infected hepatitis patients, 3 patients were associated with history of recipient blood products, 3 patients with simple TTV infection, and 5 patients of 6 with HBV/HDV and TTV co infection were recovery. [Conclusion] There is TTV infection in Quanzhou area. TTV infection can be transmitted by blood but the pathogenicity is mild. Further study should be done to explore its epidemiology and clinical significance.