| H-FABP检测对急性心肌梗死快速诊断的价值 |
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| 引用本文： | 吴飞燕,梁赋,龙静,韩朝辉,杜梅英.H-FABP检测对急性心肌梗死快速诊断的价值[J].中国热带医学,2014(6):731-732. |
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| 作者姓名： | 吴飞燕 梁赋 龙静 韩朝辉 杜梅英 |
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| 作者单位： | 海口市琼山人民医院,海南海口571100 |
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| 基金项目： | 中国高校医学期刊临床专项资金项目（No.112210831） |
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| 摘 要： | 目的探讨血清心脏型脂肪酸结合蛋白(H-FABP)检测在急诊胸痛患者的早期诊断的临床意义。方法胸痛患者135例采血测定H-FABP,并同时检测cTnI,CK-MB,联合评价其灵敏度。结果AMI组H-FABP,cTnI,CK-MB均明显高于非AMI组,差异有统计学意义(P0.01)。H-FABP灵敏度均高于cTnI,CK-MB,差异有统计学意义(P0.05)。结论H-FABP对急性心肌梗死的早期诊断具有较高的灵敏度,与cTnI、CK-MB联合检测更能提高诊断效率。
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| 关 键 词： | 胸痛患者 急性心肌梗死 心脏型脂肪酸结合蛋白 肌钙蛋白I 肌酸激酶同工酶 |
Clinical significance of detection H-FABP in rapid diagnosis of acute myocardial infarction |
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| Institution: | WU Fei-yan , LIANG Fu, LONG Jing, et al.( Qiongshan People＇s Hospital, Haikou 571100 ,Hainan, P.R.China) |
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| Abstract: | Objective To investigate significance of detection of H-FABP in rapid diagnosis of acute myocardial infarction （AMI）. Methods The 135 acute chest pain patients were divided into two groups： AMI group （45 cases） and non-AMI （90 cases）. The concentrations of H-FABP, cTnI and CK-MB in two groups were detected and compared. Results The level of H-FABP. cTnI and CK-MB in AMI group were significantly higher than that in non AMI group（P〈0.05）. Sensitivity of H-FABP in AMI group was significantly higher than that of cTnI and CK-MB （P〈0.05）. Conclusion H-FABP test is highly sensitive for early diagnosis of acute myocardial infarction and joint detection of H-FABP, cTnI and CK-MB is valuable for rapid diagnosis of acute myocardial infarction. |
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| Keywords: | Chest pain patients Acute myocardial infarction Heart- type fatty acid-binding protein（H-FABP） Cardiactroponin I （cTnI） Creatine kinase isoenzyme （CK-MB） |
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