冠心病心血管危险因素同年龄的相关性研究

目的探讨年龄与冠心病心血管危险因素的相关性。方法收集256例冠心病患者作为观察组,并以非冠心病患者132例为对照,比较两组各危险因素,并对患者按年龄分组,进行心血管危险因素的逐步Logistic回归分析。结果冠心病患者与对照组间多项心血管危险因素差异具有统计学意义(P0.05),逐步Logistic回归分析显示,年龄与冠心病发病相关(OR=0.415,95CI(0.214,0.698));青年人群中,家族史、hs-CRP、poA-I/apoB是冠心病的独立危险因素;中年组中,家族史、血脂异常、吸烟是冠心病的独立危险因素;老年组中,吸烟、家族史、高血压、血脂异常、TG、apoB、RDW、hs-CRP是冠心病的独立危险因素。结论年龄是冠心病的影响因素之一,排除年龄影响后,载脂蛋白水平可能是冠心病的独立危险因素。

Correlation of cardiovascular risk factors of coronary heart disease with age

Objective To explore the correlation between cardiovascular risk factors of coronary heart disease （CHD） with age. Methods The 256 coronary heart disease patients were investigated as observation group and 132 cases of coronary heart disease patients were treated as control group.Various risk factors assoicated with coronary heart disease were compared and analyzed. Results After comparison of multiple cardiovascular risk factors between observation group and control group statistically significant differences were noticed （P 〈 0.05）.Stepwise logistic regression analysis showed that age was associated with coronary heart disease morbidity （OR = 0.415, 95 CI （0.214, 0.698））; Among young group age, family history, levels of hs CRP, poA I/apoB were independent risk factors for coronary heart disease; In the middle age group, family history, dyslipidemia, smoking were independent risk factor for coronary heart disease, while in the elderly group, smoking, family history, hypertension, dyslipidemia, levels of TG, apoB, RDW, hs - CRP were independent risk factors for coronary heart disease. Conclusion Age is one of the influencing factors for occurrence of coronary heart disease. Excluded age the level of apolipoprotein might be an independent risk factor for coronary heart disease.