病毒性脑炎继发癫痫患者临床特点分析

目的探讨病毒性脑炎继发性癫痫患者的临床特点,以提高对该病的认识。方法回顾性分析46例病毒性脑炎继发癫痫患者的临床资料。结果 46例病毒性脑炎继发癫痫患者中37例出现影像学异常,异常率为80%。癫痫发作类型:全身性强直-阵挛发作19例(41.3%)、单纯部分性发作6例(13.04%)、复杂部分性发作7例(15.22%)、部分性发作继发全面性8例(17.39%)、持续状态6例(13.04%)。脑电图表现:呈边缘脑电图4例(8.7%)、轻度异常8例(17.39%)、中度异常20例(43.48%)、重度异常14例(30.43%)、首次脑电图检测出现癫痫波(尖波、棘波、棘-慢波综合)14例(30.43%)。结论病毒性脑炎易继发癫痫,病毒性脑炎患者应积极行影像及EEG检查。

Clinical characteristics of viral encephalitis patients with secondary epilepsy

Objective To analyze the clinical characteristics of viral encephalitis patients with secondary epilepsy. Methods The clinical data of 46 viral encephalitis patients with wsecondary epilepsy were retrospectively analyzed. Results Of the 46 viral encephalitis patients with secondary epilepsy,37 cases had abnormal finding in the cranial MRI（80%）. 19cases had GTCS attack（41.3%） in the process,6 cases had simple partial seizure（13.04%）,7 cases had complex partial seizure（15.22%）,8 cases had partial seizure evolving to secondarily generalized seizure（17.39%）, 6 cases had persistent epilepsy（13.04%）.All the patients had abnormal EEG at the beginning of onset.Conclusion The viral encephalitis tends to causesecondary epilepsy. The medical history of all the viral encephalitis patients with secondary epilepsy should be traced in detailand given imaging examination with EEG.