| 应用可视光组织氧监测急性心肌缺血模型的舌诊研究 |
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| 引用本文： | 西原辰一,史载祥,酒谷薰.应用可视光组织氧监测急性心肌缺血模型的舌诊研究[J].中国中医急症,2010,19(1):94-95. |
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| 作者姓名： | 西原辰一 史载祥 酒谷薰 |
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| 作者单位： | 1. 中日友好医院,北京,100029
2. 日本大学医学部脑神经外科 |
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| 基金项目： | 资生堂中医美容与健康研究基金赞助项目 |
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| 摘 要： | 目的观察急性心肌缺血大鼠模型的舌及心脏氧饱和度(stO2)变化以及对药物干预的反应。方法将健康SD雄性成年大鼠随机分为假手术组、模型组、西药组(美托洛尔0.2mg/kg)、大蒜素组(2.7mg/kg)、大蒜素普通脂质体组(2.7mg/kg)、大蒜素长循环脂质体组(2.7mg/kg)。制备急性心肌缺血再灌注大鼠模型,测验舌及心脏表面的stO2。结果在结扎前、给药后10min、再灌注5min时,心脏与舌比较,stO2下降更明显。从模型组能看出舌stO2在开胸手术后的各时间段与实验前比较都有明显下降。药物干预与舌stO2的影响不显著。除了假手术组以外,各组心脏stO2在结扎后和给药后,具有明显的下降,再灌注后则显著回升。结论急性心肌缺血可使舌stO2下降,但较心脏反应缓慢。本研究所选的药物对造模后stO2的影响不显著。
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| 关 键 词： | 可视光 舌诊 心肌缺血再灌注 血氧饱和度 |
Tongue Diagnosis Study of Tissue Oxygen Monitoring of Acute Myocardial Ischemia Rat Model by Visible Light |
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| Shinichi Nishihara,SHI Zai-xiang,Sakatani Kaoru.Tongue Diagnosis Study of Tissue Oxygen Monitoring of Acute Myocardial Ischemia Rat Model by Visible Light[J].Journal of Emergency in Traditional Chinese Medicine,2010,19(1):94-95. |
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| Authors: | Shinichi Nishihara SHI Zai-xiang Sakatani Kaoru |
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| Institution: | Shinichi Nishihara1,SHI Zai-xiang1,Sakatani Kaoru2 1 China-Japan Friendship Hospital ( Beijing 100029) 2 Cranial nerve surgery of Nihon University medical department |
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| Abstract: | Objective:To observe the stO2 changes of tongue and heart of acute myocardial ischemia rat model and its reaction for drug intervention. Methods: The normal SD male rats were randomly divided into sham-operated group, model group, western medicine group (metoprolol 0. 2mg / kg), garlicin group (2. 7mg / kg), garlicin conventional liposomes group (2. 7mg / kg), garlicin long circulating liposome group (2. 7mg / kg). The myocardial ischemia reperfusion rat model was established. The stO2 of its tongue and hea... |
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| Keywords: | Visible light Tongue diagnosis Myocardial ischemia reperfusion Oxygen saturation |
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