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| 微波行兔脾部分切除术后巨噬细胞吞噬功能的研究 | |
| 引用本文： | 鞠新华,夏振龙,王之章,马颖,李承斌. 微波行兔脾部分切除术后巨噬细胞吞噬功能的研究[J]. 生物医学工程学杂志, 2005, 22(6): 1238-1240 |
| 作者姓名： | 鞠新华 夏振龙 王之章 马颖 李承斌 |
| 作者单位： | 1. 中国医科大学,附属第二医院,肝胆外科,沈阳,110004 2. 中国医科大学,附属第二医院,病理科,沈阳,110004 3. 大连理工大学,电子工程系,大连,116024 |
| 摘 要： | 探讨微波在行兔脾部分切除术后对脾免疫功能的影响。微波行兔脾部分切除术(PSM)组12只和假拟手术(SO)组6只术后4周,均经耳静脉注射肺炎双球菌悬浮液,并经门静脉注射印度墨汁,全组均行脾组织切片采用H-E染色,检测巨噬细胞的吞噬功能。脾巨噬细胞的吞噬功能分级在PSM组与SO组两组间无显著性差异(P>0.05)。脾重量在两组间也无显著性差异(P>0.05)。微波行兔脾部分切除术能较好保留脾巨噬细胞的吞噬功能,提示微波行保脾手术具有一定的临床应用价值。 |
| 关 键 词： | 微波组织凝固 脾部分切除术 巨噬细胞 吞噬功能 兔 |
| 收稿时间： | 2003-06-17 |
| 修稿时间： | 2003-06-172004-02-04 |
Phagocytic Function of Macrophage after Partial Splenectomy of Rabbits Using Microwave Tissue Coagulation |
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| Ju Xinhua,Xia Zhenlong,Wang Zhizhang,Ma Ying,Li Chengbing. Phagocytic Function of Macrophage after Partial Splenectomy of Rabbits Using Microwave Tissue Coagulation[J]. Journal of biomedical engineering, 2005, 22(6): 1238-1240 | |
| Authors: | Ju Xinhua Xia Zhenlong Wang Zhizhang Ma Ying Li Chengbing |
| Affiliation: | 1.Department of General Surgery.The Second Affiliated Hospital of China Medical University, Shenyang 110004.China; 2.Department of Pathology,The Second Affiliated Hospital of China Medical University,Shenyang 110004,China; 3.Department of Electricity Engineering, Dalian University of Sciences and Technotogy,Dalian 116024,China |
| Abstract: | The immune function of spleen after partial splenectomy (PSM) of rabbits was stuided using microwave tissue coagulation(MTC).Streptococcus pneumoniae suspension was injected into the ear veins of rabbits 4 weeks after they were subjected to partial splenectomy using microwave tissue coagulation (PSM) group and to sham operation(SO groups),respectively.India ink was given via portal vein.Residual spleen were resected and microscopic examinations were performed on spleen slices stained using HE to compare phagocytic functions of macrophage.Gradings of phagocytic function in macrophage were of no significant difference between PSM and SO groups(P>0.05).Weights of spleens showed no significant difference between the two groups(P>0.05).The phagocytic function of macrophage after PSM can be preserved well.The result of this experiment implies that splenic salvage using MTC is a clinically applicable method. |
| Keywords: | Microwave tissue coagulation(MTC) Partial splenectomy Macrophages Phagocytic function Rabbits |
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